Proventriculitis was studied by experimentally reproducing the disease in broiler chickens. One-day-old infectious bursal disease virus (IBDV) and infectious bronchitis virus (IBV) antibody positive commercial broilers and 1-day-old antibody negative specific-pathogen-free (SPF) broilers were orally gavaged with proventricular homogenates produced from the proventriculi of broilers with provent...

A search for dominant-negative mutant polypeptides hampering infectious bursal disease virus (IBDV) replication has been undertaken. We have found that expression of a mutant version of the VP3 structural polypeptide known as VP3/M3, partially lacking the domain responsible for the interaction with the virus-encoded RNA polymerase, efficiently interferes with the IBDV replication cycle. Transfo...

The early and accurate diagnosis of infectious bursal disease requires known hyperimmune serum against the disease. In this study, an attempt was made to raise anti-infectious bursal disease virus hyperimmune serum in rabbits. The infectious bursal disease (IBD) virus was isolated from field outbreaks, identified, purified, titrated and its infectivity titre was determined in embryonated eggs. ...

An outbreak of inclusion body hepatitis was noticed in 20% of the population of a flock of 20000 broiler chickens. The affected 14-day-old birds experienced 10% mortality during a period of one week. On 39 and 44 days of age, clinical infectious bursal disease and Newcastle disease with 5% and 15% mortalities occurred in the flock, respectively. Clinical signs of affected birds included depress...

Here, we report the complete coding genome sequence of a novel reassortant and very virulent infectious bursal disease virus (IBDV), designated JBN2011. Characterization of the JBN2011 genome suggests that it is a rare recombinant virus having a very virulent IBDV segment A and a Bursine-2-like attenuated IBDV segment B.