Oxidative stress (OS) occurs with an overabundance of reactive oxygen species (ROS) generation and the inability of scavengers, i.e. antioxidants, to neutralize excessive loads of ROS. OS has a role in the etiopathologenesis of many factors causing natural infertility. Infertility is a problem of great magnitude affecting 6 million American women. The etiologies of unexplained infertility and r...

Background and Objectives: Infertility is a global health issues. Inability to have child stressful affects all aspects of couple’s lives. The aim the study was assess level stress among women with infertility. Materials Methods: A non-experimental, uni-variant descriptive survey design used which included 200 infertile in two infertility centres Dehradun. self-developed Likert scale administer...

Whereas it is well established that chronic stress induces female reproductive dysfunction, whether stress negatively impacts fertility and fecundity when applied prior to mating and pregnancy has not been explored. In this study, we show that stress that concludes 4 days prior to mating results in persistent and marked reproductive dysfunction, with fewer successful copulation events, fewer pr...

Male infertility continues to be a clinical challenge of increasing significance. While male factors such as decreased semen quality are responsible for 25% of all infertility issues, the etiology of suboptimal semen quality is poorly understood. Many physiological, environmental, and genetic factors have been implicated, including oxidative stress. Oxidative stress is induced by reactive oxyge...

BACKGROUND Attachment style may influence distress and relationship satisfaction in infertile couples. Appraisal and coping have also been linked to adjustment to infertility and may be related to attachment patterns. The study examined these associations in men and women around the time of attending initial appointments at fertility clinics. METHODS Attachment, appraisal, coping, general wel...

Cisplatin causes infertility due to ovarian toxicity. The toxicity mechanism is unknown, but evidence suggests oxidative stress. In this study, the effect of mirtazapine on cisplatin-induced infertility and oxidative stress in rats was investigated. 64 female rats were divided into 4 groups of 16. Except for the controls that received physiologic saline only, all were administered with cisplati...

Research shows that men diagnosed with male factor infertility experience more suffering than men with infertility due to other causes, and that it is socially unfavourable to be diagnosed with male factor infertility resulting in secrecy surrounding diagnosis, sometimes to the point that women take the blame for the couples' infertility. We investigated mental and physical health, support, and...

Infertility is a common problem experienced by many couples. Numerous treatments are available for female infertility. However, in some cases, the treatment is empirical in nature because the aetiology of infertility is not fully understood. Recently, reactive oxygen species (ROS) have been shown to have an important role in the normal functioning of reproductive system and in the pathogenesis ...