Mammary stem cells provide for growth and maintenance of the mammary gland and are therefore of considerable interest as determinants of productivity and efficiency of dairy animals and as targets of carcinogenesis in humans. Xanthosine treatment was previously shown to promote expansion of hepatic stem cells in vitro. The objective of this study was to determine if in vivo treatment with xanth...

The present review shows a modern view on the issues of differential ultrasound diagnosis hyperechoic malignant tumors mammary glands. On clinical examples, main ultrasonic semiotic signs structures were noted in comparison with data histopathological analysis.

Lactoferrin (Lf) is an iron-binding glycoprotein that is produced by mucosal epithelial cells in mammals. Lf has non-immune natural defense functions and biological functions in addition to and distinct from its role in regulating inflammatory responses. Lf also improved some physiological and immunological parameters. Lf is a biomarker for monitoring medical treatment in inflammatory bowel dis...

Aberrant expression of several cyclin genes has been demonstrated to be associated with many types of tumors. To determine the capacity of cyclin A to function as an oncogene in vivo, wild-type and mutant cyclin A proteins were specifically overexpressed in the mammary glands of transgenic mice using regulatory sequences from the ovine beta-lactoglobulin gene. Several lines of transgenic mice w...

BACKGROUND Infrared thermography is a painless, noninvasive, nonionizing diagnostic imaging exam used in human medicine as an auxiliary tool for breast cancer diagnosis in women. HYPOTHESIS/OBJECTIVES Define thermographic mean temperatures of healthy mammary glands and compare these temperatures with those of mammary glands with tumors in dogs. ANIMALS Fifty client-owned female dogs were ev...

Vitásek R. , H. Dendisová: Treatment of Feline Mammary Fibroepithelial Hyperplasia Following a Single Injection of Proligestone. Acta Vet. Brno 2006, 75: 295-297. A case of fibroepithelial hyperplasia of the mammary gland in the cat is reported. A seven-monthold female cat was presented for diffuse enlargement of all of the mammary glands. The cat was treated with proligestone (Covinan®) for th...

objectives: in traditional medicine salvia officinalis (sage) has been used as menstrual cycle regulator. in the present study the effects of sage extract on breast tissue were examined. materials and methods: fourteen female rats were divided into two groups: 1) distilled water-treated rats (con) that were gavaged with 1ml distilled water and 2) saliva officinalis hydroalcoholic extract (she)-...

Certain straiiis of mice are particularly susceptible to the development of spontaneous mammary gland adenocarcinoma. Other straiiis show a marked resistance to such atypical growths. The predisposition to tumor development thus appears to be determined at least part ially by hereditary fact or s. That the predisposition to tumor incidence might be determined or indicated by structural or devel...

In a large Kenyan production unit the urogenital organs and mammary glands of 771 sows, culled due to recurring swine urogenital disease (SUGD) were subjected to necropsy Necropsy findings were analysed separately according to parity group of the sows [parities 2 (n = 252); 3-5 (n = 250); and > 5 (n = 269)]. Sows of higher parities had more pathological changes in their ovaries, uteri, vaginas,...