نتایج جستجو برای: inflammatory drug

تعداد نتایج: 822379  

Journal: :Journal of Drug Delivery and Therapeutics 2021

Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder of the small intestine colon. IBD includes ulcerative colitis (UC) Crohn’s (CD), it main reason for expansion colon cancer, referred to as colitis-associated cancer (CAC). Oral colon-targeted microsphere based drug delivery system containing sulfasalazine was prepared, optimized characterized. The micros...

Journal: :iranian journal of pharmacology and therapeutics 0
ram lal lodhi shubhini a. saraf gaurav kaithwas sudipta saha assistant professor, department of pharmaceutical sciences, babasaheb bhimrao ambedkar university, vidya vihar, rai barely road, lucknow 226025, lucknow

leflunomide (lef), used for rheumatoid arthritis, inhibits dihydro-orotate dehydrogenase (dhodh) and tyrosine kinase (tk) enzymes and has anti-inflammatory, lymphocyte proliferation regulatory, immunosuppression and chondroprotective effects. the most common adverse effects are gastrointestinal disorders, weight loss, hypertension, skin infection, and neurological and hematological toxicity. it...

2016
Kazuhide Inage Sumihisa Orita Kazuyo Yamauchi Takane Suzuki Miyako Suzuki Yoshihiro Sakuma Go Kubota Yasuhiro Oikawa Takeshi Sainoh Jun Sato Kazuki Fujimoto Yasuhiro Shiga Koki Abe Hirohito Kanamoto Masahiro Inoue Hideyuki Kinoshita Kazuhisa Takahashi Seiji Ohtori

STUDY DESIGN Retrospective study. PURPOSE To determine whether low-dose tramadol plus non-steroidal anti-inflammatory drug combination therapy could prevent the transition of acute low back pain to chronic low back pain. OVERVIEW OF LITERATURE Inadequately treated early low back pain transitions to chronic low back pain occur in approximately 30% of affected individuals. The administration ...

ghesmati, Masoumeh, Vakili, Marjan ,

Drug-induced acute interstitial nephritis (DI-AIN) is a common cause of AKI and leading to CKD and ESRD Although any drug can potentially cause DI-AIN, antibiotics, non-steroidal anti-inflammatory drugs and proton pump inhibitors are the most common culprits. In the present study, we report a 9-year-old child with drug-induced interstitial nephritis (cefotaxime, vancomycin, and acyclovir). it s...

Diclofenac sodium has been used for its anti-inflammatory actions for about 28 years, but since all the non-steroidal anti-inflammatory drugs (NSAIDs) suffer from the lethal gastro intestinal (GI) toxicities, diclofenac sodium is not an exception. The free –COOH group is thought to be responsible for the GI toxicity associated with all traditional NSAIDs. In the present research, the main motto...

Physalis angulata is a medicinal plant used for the treatment of malaria, ulcer, pains and other diverse ailments. The present study evaluated the analgesic and anti-inflammatory activity of methanolic leaf extract of the plant. Acetic acid-induced abdominal contraction or writhing analgesic models in Swiss albino mice (13-23g) were used for studying analgesic activity of the leaf extract. 200,...

Journal: :jentashapir journal of health research 0
eskandar moghimipour anayatollah salimi anayatollah salimi haj mohammadi haj mohammadi haj mohammadi

background indomethacin is a nsaid (non-steroidal anti-inflammatory drug) that is used in treatment of pain and inflammatory. immediate and sustained release products of this drug have side effects, so a proper replacement is needed. use of the medicine via topical and cutaneous routs has advantages such as avoiding side effects on gastrointestinal; and supplying an amount of medicine in plasma...

Journal: :iranian journal of pharmaceutical research 0
a pandurangan rl khosa s hemalatha

methanolic extract of solanum trilobatum linn. (mest) belonging to the family of solanacea was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its anti-inflammatory activity by subjecting into carrageenan, and cotton pellet induced granuloma tests for its effect on acute and chronic phase inflammation models in...

Diclofenac sodium has been used for its anti-inflammatory actions for about 28 years, but since all the non-steroidal anti-inflammatory drugs (NSAIDs) suffer from the lethal gastro intestinal (GI) toxicities, diclofenac sodium is not an exception. The free –COOH group is thought to be responsible for the GI toxicity associated with all traditional NSAIDs. In the present research, the main motto...

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