Recently, the association of Th-17 cells or IL-17 with ocular inflammatory diseases such as uveitis, scleritis and dry eye syndrome was discovered. We assessed whether interleukin (IL)-17 was present in the tears of various ocular surface inflammatory diseases and the tear IL-17 concentrations were clinically correlated with various ocular surface inflammatory diseases. We measured concentratio...

inflammatory bowel disease (ibd) is an irregular response of immune system accompanied with different inflammatory manifestations including alterations in cytokines. probiotics are non-pathogenic organisms with probable effects in various conditions such as inflammation. the present study hypothesized whether oral intake of bifidobacterium and lactobacillus in form of probiotic yogurt may repre...

the aim of this study was to test the therapeutic efficacy of sodium alginate in a rat model of trinitrobenzene sulfonic acid (tnbs)-induced inflammatory bowel disease. this experiment was carried out using 77 sprague-dawley rats which were divided into six groups; normal, control, prophylactic, therapeutic and two experimental groups. rats were sacrificed 1, 2, 3 and 6 weeks after colitis indu...

background the incidence of inflammatory bowel disease (ibd) varies among different societies. the aim of this study is to determine the incidence rate of ibd in kerman, a city in southeast iran. methods all medical records that indicated a new diagnosis of ulcerative colitis (uc) or crohn`s disease (cd) were retrieved from the gastrointestinal endoscopy and pathology departments of 12 centers ...

background: minimal bright red bleeding per rectum (mbrbpr) is a common complaint in adult patients. most studies have not been performed in patients with strictly minimal brbpr, and there are no evidence-based recommendations for this group of patients. materials and methods: patients with complaints as small amounts of red blood after wiping or a few drops of blood in the toilet bowl after de...

background:   case: we discuss 3 clinical cases of tubo-ovarian abscess in women with endometriosis after oocyte retrieval despite antibiotic prophylaxis between 2004 and 2011 at our center, and discuss our experience in the context of earlier reports.   conclusion: it is unclear whether antibiotic prophylaxis is necessary in these women, and which antibiotic is best. only douching with povidon...

background: evidence has shown a link between allergic disease and inflammatory bowel diseases (ibds). we investigated food allergy in iranian pediatric ibd patients. materials and methods: a cross-sectional study was conducted on a consecutive sample of children with newly  diagnosed ibd referring to mofid children’s university hospital in tehran (iran) between november 2013 and march 2015.dat...

Onchocerciasis is a major cause of blindness. Although the World Health Organization has been successful in reducing onchocerciasis as a public health problem in parts of West Africa, there remain an estimated 17 million people infected with Onchocerca volvulus, the parasite that causes this disease. Ocular pathology can be manifested in any part of the eye, although disease manifestations are ...

Thyroid eye disease (also known as Graves' ophthalmopathy) is a complex orbital inflammatory disease, which can be sight threatening, debilitating and disfiguring. This overview discusses the epidemiology, risk factors, pathogenesis, presentation, ophthalmic clinical features, investigations and treatment of thyroid eye disease.

Dry eye is a common eye disease, and suitable animal models are indispensable for investigating the pathogenesis and developing treatments for dry eye. The present study was conducted to develop an androgen deficiency dry eye model induced by finasteride, and to evaluate ocular surface status and inflammatory cytokine gene expression in the lacrimal gland using a cytokine antibody array system....