نتایج جستجو برای: influenza a h7n9 virus

تعداد نتایج: 13592173  

Journal: :Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2014
D Wang L Yang R Gao X Zhang Y Tan A Wu W Zhu J Zhou S Zou Xiyan Li Y Sun Y Zhang Y Liu T Liu Y Xiong J Xu L Chen Y Weng X Qi J Guo Xiaodan Li J Dong W Huang L Dong X Zhao L Liu J Lu Y Lan H Wei L Xin Y Chen C Xu T Chen Y Zhu T Jiang Z Feng W Yang Y Wang H Zhu Y Guan G F Gao D Li J Han S Wang G Wu Y Shu

A novel avian influenza A(H7N9) virus causing human infection emerged in February 2013 in China. To elucidate the mechanism of interspecies transmission, we compared the signature amino acids of avian influenza A(H7N9) viruses from human and non-human hosts and analysed the reassortants of 146 influenza A(H7N9) viruses with full genome sequences. We propose a genetic tuning procedure with conti...

2014
Ahmed Salem El Arbi Ahmed Bezeid El Mamy Habib Salami Ekatarina Isselmou Olivier Kwiatek Geneviève Libeau Yaghouba Kane Renaud Lancelot

were positive for the hemagglutinin (HA) and neuraminidase genes of avian influenza A (H7N9) virus. Of 6 environmental samples, 5 were positive for (H7N9) virus HA genes. No (H7N9) virus HA antibodies were detected from paired serum samples from all 18 close contacts. Two virus strains were isolated: 1 from a patient specimen (A/Zhenjiang/1/2013) and 1 from a chicken cage specimen (A/environmen...

2014
Jeremy C. Jones Stephanie Sonnberg Zeynep A. Koçer Karthik Shanmuganatham Patrick Seiler Yuelong Shu Huachen Zhu Yi Guan Malik Peiris Richard J. Webby Robert G. Webster

Avian-origin influenza A(H7N9) recently emerged in China, causing severe human disease. Several subtype H7N9 isolates contain influenza genes previously identified in viruses from finch-like birds. Because wild and domestic songbirds interact with humans and poultry, we investigated the susceptibility and transmissibility of subtype H7N9 in these species. Finches, sparrows, and parakeets suppor...

2014
Rui Huang Lu Zhang Qin Gu Yi-Hua Zhou Yingying Hao Kui Zhang Yong Liu Danjiang Dong Shixia Wang Zuhu Huang Shan Lu Chao Wu

The influenza A H7N9 virus outbreak in Eastern China in the spring of 2013 represented a novel, emerging avian influenza transmission to humans. While clinical and microbiological features of H7N9 infection have been reported in the literature, the current study investigated acute cytokine and antibody responses in acute H7N9 infection. Between March 27, 2013 and April 23, 2013, six patients wi...

2014
Jian Fan David Cui Siuying Lau Guoliang Xie Xichao Guo Shufa Zheng Xiaofeng Huang Shigui Yang Xianzhi Yang Zhaoxia Huo Fei Yu Jianzhou Lou Li Tian Xuefen Li Yuejiao Dong Qiaoyun Zhu Yu Chen

BACKGROUND A novel avian influenza A (H7N9) virus emerged in eastern China in February 2013. 413 confirmed human cases, including 157 deaths, have been recorded as of July 31, 2014. METHODS Clinical specimens, including throat swabs, sputum or tracheal aspirates, etc., were obtained from patients exhibiting influenza-like illness (ILIs), especially from those having pneumonia and a history of...

Journal: :Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2014
Z Meng R Han Y Hu Z Yuan S Jiang X Zhang J Xu

Avian influenza A(H7N9) virus re-emerged in China in December 2013, after a decrease in the number of new cases during the preceding six months. Reassortment between influenza A(H7N9) and local H9N2 strains has spread from China's south-east coast to other regions. Three new reassortments of A(H7N9) virus were identified by phylogenetic analysis: between A(H7N9) and Zhejiang-derived strains, Gu...

Journal: :Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2014
Mai-Juan Ma Xiao-Xian Yang Xian Xia Benjamin D Anderson Gary L Heil Yan-Hua Qian Bing Lu Wu-Chun Cao Gregory C Gray

BACKGROUND Avian H7N9 virus emerged in China in February 2013 and has since spread widely among China's poultry, causing numerous human infections. OBJECTIVES To compare World Health Organization (WHO) and US commercial influenza assays in detecting avian H7N9 virus in poultry cloacal specimens. STUDY DESIGN Between April 6 and July 15, 2013, 261 cloacal swabs were collected from commercial...

2014
Penghui Yang Hongjing Gu Zhongpeng Zhao Wei Wang Bin Cao Chengcai Lai Xiaolan Yang LiangYan Zhang Yueqiang Duan Shaogeng Zhang Weiwen Chen Wenbo Zhen Maosheng Cai Josef M. Penninger Chengyu Jiang Xiliang Wang

Since March 2013, the emergence of an avian-origin influenza A (H7N9) virus has raised concern in China. Although most infections resulted in respiratory illness, some severe cases resulted in acute respiratory distress syndrome (ARDS), which is a severe form of acute lung injury (ALI) that further contributes to morbidity. To date, no effective drugs that improve the clinical outcome of influe...

2014
Juan Ayllon Patricia Domingues Ricardo Rajsbaum Lisa Miorin Mirco Schmolke Benjamin G. Hale Adolfo García-Sastre T. S. Dermody

Although an effective interferon antagonist in human and avian cells, the novel H7N9 influenza virus NS1 protein is defective at inhibiting CPSF30. An I106M substitution in H7N9 NS1 can restore CPSF30 binding together with the ability to block host gene expression. Furthermore, a recombinant virus expressing H7N9 NS1-I106M replicates to higher titers in vivo, and is subtly more virulent, than t...

2014

This document describes options for mitigating human exposure to the avian influenza A(H7N9) virus via birds and their by-products, and options for mitigating the spread of H7N9 in birds. It applies both to countries where H7N9 exists and to those that have not yet identified the virus. It should be read in conjunction with FAO’s current H7N9 risk assessment and surveillance guidelines and will...

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