background: in this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to mahak pediatric cancer treatment and research center (one of the main national referral centers for childhood malignancies in iran) for treatment. materials and methods: this cohort (simple sampling) study consisted of 198 children less than 15 year old with cns tumor refer...

BACKGROUND AND PURPOSE Migraine is a risk factor for clinical stroke and for subclinical white matter hyperintensities and infratentorial infarcts. These subclinical lesions are linked to small-vessel pathology. Cerebral microbleeds (CMBs) are another biomarker of small-vessel disease but have not yet been studied in migraine. METHODS Identification of CMBs in 63 migraineurs (25 with aura/35 ...

The anatomic extent of brain stem damage may provide information about clinical outcome and prognosis in children with hypoxic-ischemic encephalopathy and oral motor dysfunction. The aim of this study was to retrospectively characterize the location and extent of brain stem lesions in children with oral motor dysfunction. From January 2005 to August 2009, 43 infants hospitalized at our institut...

OBJECTIVES To determine the sensitivity, specificity, and positive predictive values of a selection of abnormal findings in the putamen and infratentorial structures on routine magnetic resonance imaging for distinguishing between multiple system atrophy, idiopathic Parkinson's disease, and age matched controls. PATIENTS AND METHODS Two neuroradiologists blindly and independently rated axial ...

A teenage girl with a chronic large posterior fossa tumor had primary position right-beating nystagmus with a constant-velocity slow phase. Smooth pursuit was normal to the left but absent to the right. Vestibuloocular move­ ments were present in both directions. The findings are analogous to downbeat and upbeat nystagmus, in which unidirectional pursuit palsies have been postulated as the path...

BACKGROUND AND PURPOSE Site-specific degeneration patterns of the infratentorial brain in relation to phylogenetic origins may relate to symptoms in patients with spinocerebellar degeneration, but the patterns are still unclear. We investigated macro- and microstructural changes of the infratentorial brain based on phylogenetic origins and their correlation with symptoms in patients with spinoc...

OBJECTIVE Based on surgical outcomes of patients with infratentorial meningiomas surgically treated at our institution, we analyzed the predictors for surgical resection, recurrence, complication, and survival. METHODS Of surgically treated 782 patients with intracranial meningioma, 158 (20.2%) consecutive cases of infratentorial location operated on between April 1993 and May 2013 at out ins...