DEET (N,N-diethyl-meta-toluamide) is the world's most widely used topical insect repellent, with broad effectiveness against most insects. Its mechanism of action and molecular target remain unknown. Here, we show that DEET blocks electrophysiological responses of olfactory sensory neurons to attractive odors in Anopheles gambiae and Drosophila melanogaster. DEET inhibits behavioral attraction ...

Plant derivatives possessing insect repellent and antifeedant properties could offer an alternative approach for managing crop pests and dealing with insect-transmitted diseases. This chapter summarizes results from studies on insecticidal effects of Melia azedarach extracts from Central Argentina. Extracts from different plant structures (green/ripe fruits, green/senescent leaves) and a variet...

A number of preventive measures for the protection of humans against tick-borne diseases were evaluated. Measures involving the avoidance of tick bites with the use of protective clothing and insect repellents are the simplest and most effective. Repellents are applied directly to the skin or clothing and other fabrics, such as bednets, tents and anti-mosquito screens. Currently, DEET (N,N-diet...

Abstract Pest is primary main destructive agents in fruits and vegetable production that impact the quality its production. Insect pests are most ruinous attack plants. Use of chemical pesticides has become extensive to reduce losses. However, synthetic can have adverse effects on environment human if applied without proper training pesticide application. One alternative ways control environmen...

Catnip (Nepeta cataria) is known for its pseudo-narcotic effects on cats. Recently, it has been reported as an effective mosquito repellent against several Aedes and Culex species, both topically and spatially. Our laboratory bioassays showed that catnip essential oil (at a dosage of 20 mg) resulted in average repellency rates of 96% against stable flies, Stomoxys calcitrans (L.) and 79% agains...

Today, Insect Pest management (IPM) has to face up to the economic and ecological consequences of the use of pest control measures. Fifty years of sustained struggle against harmful insects using synthetic and oil-derivative molecules has produced perverse secondary effects (mammalian toxicity, insect resistance and ecological hazards). The diversification of the approaches inherent in IPM is n...

Textile materials treated with synthetic repellents have the potential to provide protection against insect disease vectors but lack the residual activity necessary to achieve a prolonged effect or to be cost-effective. DEET MC is a formulation of DEET (N,N diethyl-m-toluamide) in which the repellent is gradually released from a capsule that binds the repellent. An experiment carried out on DEE...

♦ Personal protective measures, such as using insect repellent, wearing longsleeved shirts and long pants while outdoors, and avoiding tick and mosquito habitat, reduce the risk of vector-borne diseases. Vector-borne Diseases in Hennepin County Key Findings Introduction This Epidemiology Update summarizes vector-borne disease cases and trends in Hennepin County. This issue is one in a series of...