GRODSKY, GEROLD M., ADRIENNE A. BATTS, LESLIE L. BENNETT, CARL VCELLA, NANCY B. MCWILLIAMS, AND DESMOND F. SMITH. Effects uj carbohydrates on secretion of insulin from isolated rut pancreas. Am. J, Physiol. 205(4) : 638-644. Ig63.-The effect of carbohydrates on the secretion of immunochemically measurable insulin was studied in an isolated perfused pancreatic preparation from the rat. Degradati...

GRODSKY, GEROLD M., ADRIENNE A. BATTS, LESLIE L. BENNETT, CARL VCELLA, NANCY B. MCWILLIAMS, AND DESMOND F. SMITH. Effects uj carbohydrates on secretion of insulin from isolated rut pancreas. Am. J, Physiol. 205(4) : 638-644. Ig63.-The effect of carbohydrates on the secretion of immunochemically measurable insulin was studied in an isolated perfused pancreatic preparation from the rat. Degradati...

BACKGROUND Model-based glycemic control relies on sufficiency of underlying models to describe underlying patient physiology. In particular, very preterm infant glucose-insulin metabolism can differ significantly from adults, and is relatively unstudied. In this study, C-peptide concentrations are used to develop insulin-secretion models for the purposes of glycemic control in neonatal intensiv...

BACKGROUND Insulin secretion correlates inversely with insulin sensitivity, which may suggest the existence of a crosstalk between peripheral organs and pancreas. Such interaction might be mediated through glucose oxidation that may drive the release of circulating factors with action on insulin secretion. AIM To evaluate the association between whole-body carbohydrate oxidation and circulati...

the aim of this research was to determine the effects of carbohydrate and branched chain amino acid supplements consumption in recovery period on secretion of insulin and preserving the performance of wrestlers. for this purpose, 21 wrestlers in zanjan team (mean age: 20.07?1.93 years, height: 171?5.37 cm, weight: 65.38?6.39 kg, vo2max: 65.73?3.94 ml/kg/min and insulin before bruce test: 14.13?...

conclusions according to the results, ud is able to decrease glucose level and improve insulin release in t2dm. in addition, as ud is able to induce a small increase in ampk activity, it is possible that the anti-hyperglycemic effect of ud is mediated by insulin secretion and the possible changes in ampk levels. results fbg levels of the drug group were significantly decreased compared with the...

The strain of athymic nude male mice (ANM) developed at the University of Southern California (USC) exhibits spontaneous hyperglycemia and relative hypoinsulinemia in vivo. To investigate factors that influence insulin secretion in this animal model of non-insulin-dependent diabetes mellitus, we utilized the isolated perfused mouse pancreas of the ANM-USC and control BALB/c mice. We compared in...

Insulin secretion tests were carried out before and after treatment in patients with severe congestive heart failure. Before treatment the plasma insulin level and the insulin secretion response to intravenous tolbutamide were significantly reduced in all patients. In patients who made a good clinical recovery the plasma insulin level and the insulin secretion response were significantly improv...

BACKGROUND A fundamental precept of the carbohydrate-insulin model of obesity is that insulin secretion drives weight gain. However, fasting hyperinsulinemia can also be driven by obesity-induced insulin resistance. We used genetic variation to isolate and estimate the potentially causal effect of insulin secretion on body weight. METHODS Genetic instruments of variation of insulin secretion ...

Objective: Insulin secretion and insulin resistance are associated with incidence and severity of type 2 diabetes mellitus (T2DM). This study aimed to assess the effect of high intensity intermittent training (HIIT) on GLP-1R expression in pancreas tissue and serum insulin of T2DM rats. Materials and Methods: In this quasi-experimental study, T2DM induced by intraperitoneal injection of strept...