AIMS Unsatisfactory effects of therapeutic angiogenesis in critical limb ischaemia may be ascribed to use of circulating angiogenic cells (CACs) derived from atherosclerotic patients with impaired neovascularization-related capacities. We tested whether ultrasound cell stimulation can restore the impaired capacities. METHODS AND RESULTS During culture of human peripheral blood-derived mononuc...

STUDY DESIGN In vitro experimental study. OBJECTIVE To investigate the effect of low-intensity pulsed ultrasound (LIPUS) on the extracellular matrix (ECM) synthesis of degenerative human nucleus pulposus cells and explore the molecular mechanism. SUMMARY OF BACKGROUND DATA LIPUS has been used successfully for bone fracture healing and been proved to be effective in stimulating ECM metabolis...

The purpose of this study was to determine whether low-intensity pulsed ultrasound (LIPUS) could enhance the regeneration of myofibers and shorten the healing time in injured muscle. NIH C2C12 cells, a well-known myoblastic cell line, are subclones derived from the mouse myoblast cell line established from normal adult C3H mouse leg muscle. The cells differentiate rapidly and produce extensive ...

The present study was designed to determine the underlying mechanism of low-intensity pulsed ultrasound (LIPUS) induced alveolar bone remodeling and the role of BMP-2 expression in a rat orthodontic tooth movement model. Orthodontic appliances were placed between the homonymy upper first molars and the upper central incisors in rats under general anesthesia, followed by daily 20-min LIPUS or sh...

The protein expressions of neurotrophic factors can be enhanced by low-intensity pulsed ultrasound (LIPUS) stimulation in the brain. The purpose of this study was to demonstrate the protective effect of LIPUS stimulation against aluminum-induced cerebral damage in Alzheimer's disease rat model. LIPUS was administered 7 days before each aluminum chloride (AlCl3) administration, and concomitantly...

Ultrasound is a form of mechanical energy with its acoustic pressure wave at frequencies range from 20 to 20,000 Hz. To date, ultrasound waves are not only used in imaging medicine for diagnosis, but also are performed in physical therapy (PT) medicine for the purpose of preventing and curing disease due to its thermal and nonthermal effects, and the ultrasound frequencies used in PT are typica...

Ultrasound is a form of mechanical energy with its acoustic pressure wave at frequencies range from 20 to 20,000 Hz. To date, ultrasound waves are not only used in imaging medicine for diagnosis, but also are performed in physical therapy (PT) medicine for the purpose of preventing and curing disease due to its thermal and nonthermal effects, and the ultrasound frequencies used in PT are typica...

BACKGROUND Low-intensity pulsed ultrasound (LIPUS) has presented good results in the healing of chronic wounds. The objective of this study was to compare the effect of LIPUS on the viability of transverse rectus abdominal muscle (TRAM) flap in different regions (central and epigastric) in rats. METHODS Twenty-one Wistar male rats were homogeneously distributed into three groups as follows: g...