نتایج جستجو برای: interlukine 37
تعداد نتایج: 121481 فیلتر نتایج به سال:
Lung cancer is still the number one cause of death from cancer worldwide. The clinical effect of platinum-based chemotherapy for non-small cell lung cancer is constrained by the resistance to drug. To overcome chemo-resistance, various modified treatment including combination therapy has been used, but overall survival has not been improved yet. In this study, chemo-resistant lung cancer cells,...
This review considers the definition of a healthy bone phenotype through the life course and the modulating effects of muscle function and nutrition. In particular, it will emphasise that optimal bone strength (and how that is regulated) is more important than simple measures of bone mass. The forces imposed on bone by muscle loading are the primary determinants of musculoskeletal health. Any f...
Although lumbar instability is considered to be responsible for the majority of chronic or recurrent backaches, the word ‘instability’ is still poorly defined. A number of different definitions exist, but as yet there are no clear and validated clinical features by which instability might be diagnosed. It is also not clear how instability as such might set up pain and disability. It is generall...
Recent studies in laboratory rodents have revealed that circadian oscillation in the physiologic functions affecting drug disposition underlies the dosing time-dependent change in pharmacokinetics. However, it is difficult to predict the circadian change in the drug pharmacokinetics in a diurnal human by using the data collected from nocturnal rodents. In this study, we used cynomolgus monkeys,...
This paper presents an evolutionary growth theory that captures the interplay between the evolution of mankind and economic growth since the emergence of the human species. This uni"ed theory encompasses the observed evolution of population, technology and income per capita in the long transition from an epoch of Malthusian stagnation to sustained economic growth. 2001 Elsevier Science B.V. All...
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