Numerical methods for the simulation of radiation transport, in particular Monte Carlo techniques, are playing a fundamental role in the field of dosimetry for radiation protection. For the last 30 years or so, reference quantities have been since about 30 years calculated relying on mathematical analytical human phantoms representative of the standard man. These calculations, in large part bas...

BACKGROUND Coincidence imaging of low-abundance yttrium-90 (90Y) internal pair production by positron emission tomography with integrated computed tomography (PET/CT) achieves high-resolution imaging of post-radioembolization microsphere biodistribution. Part 2 analyzes tumor and non-target tissue dose-response by 90Y PET quantification and evaluates the accuracy of tumor 99mTc macroaggregated ...

Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Portugal In order to ensure the safe usage of new radiopharmaceuticals in Positron Emission Tomography (PET), it is necessary to quantify the doses delivered to the organs and tissues within the patients’ bodies. A framework that allows estimating the dose delivered by PET has been established by the MIRD Committee ...

Background: Whole-body counters are widely used to evaluate internal contamination of the internal presence of gamma-emitting radionuclides. In internal dosimetry, it is a basic requirement that quality control procedures be applied to verify the reliability of the measured results. The implementation of intercomparison programs plays an important role in quality control, and the accuracy of th...

A new numerical method for solving the inverse problem of internal dosimetry is described. The new method uses Markov Chain Monte Carlo and the Metropolis algorithm. Multiple intake amounts, biokinetic types, and times of intake are determined from bioassay data by integrating over the Bayesian posterior distribution. The method appears definitive, but its application requires a large amount of...

Abstract Dosimetry models for the estimation of particle deposition in human respiratory tract (RT) conjunction with clearance transport are vital components to relate exposure internal dose a quantitative manner. The current work highlights knowledge and modelling approaches on translocation body an effort determine health risks respect different physicochemical properties physiology parameter...

Computational phantoms are commonly used in internal radiation dosimetry to assess the amount and distribution pattern of energy deposited in various parts of the human body from different internal radiation sources. Radiation dose assessments are commonly performed on predetermined reference computational phantoms while the argument for individualized patient-specific radiation dosimetry exist...