INTRODUCTION Endothelial dysfunction and increased intima-media thickness are early findings in the development of atherosclerosis that can be assessed non-invasively by echography. The aim of this study was to investigate endothelial function and intima-media thickness, and the relation between these processes and cardiovascular risk factors in patients without clinical atherosclerosis. PATI...

The aims of this study are to describe the mean values of carotid intima-media thickness and how it increases with age, and to compare carotid injury in diabetics and hypertensive patients with that of controls. We included 562 subjects (121 diabetics, 352 hypertensive patients, 89 controls). The mean intima-media thickness was 0.781 mm in diabetics, 0.738 mm in hypertensive patients and 0.686 ...

although the etiology of varicose veins remains unknown, recent studies have focused on endothelial cell integrity and function because the endothelium regulates vessel tone and synthesizes many pro- and anti-inflammatory factors. the aim of this study was to investigate the evidence involving the endothelium in the development of varicose vein disease. in addition, tissue remodeling was invest...

Measurement of the carotid intima-media thickness enables arterial wall thickening to be quantified during preclinical disease stages. However, little is known about how the thickness varies in individuals with no cardiovascular risk factors. The objective of this study was to report on the range of carotid intima-media thicknesses observed in a population of healthy subjects with no cardiovasc...

OBJECTIVE We demonstrated that inflammatory cells and intima-media thickening are increased in carotids exposed to low-blood flow in the SJL/J (SJL) strain compared with other mouse strains. We hypothesized that the extent of inflammation associated with intima-media thickening is a genetically regulated trait. APPROACH AND RESULTS We performed a whole genome approach to measure leukocyte inf...

Intima-media thickness (IMT) of the common carotid artery is routinely measured in ultrasound images and its increase a marker pathology. Manual measurement being subject to substantial inter- intra-observer variability, automated methods have been proposed find contours intima-media complex (IMC) deduce IMT thereof. Most them assume that these are smooth curves passing through points with stro...

conclusions high prevalence of the increased cimt in patients undergoing cabg highlights the significance of cimt measurement in early diagnosis of the systemic atherosclerosis. moreover, although traditional cardiovascular risk factors were important they could not explain the extension and the severity of cimt. it seems that some ultrasonographic features such as the associated carotid plaque...

BACKGROUND The combined thickness of the intima and media of the carotid artery is associated with the prevalence of cardiovascular disease. We studied the associations between the thickness of the carotid-artery intima and media and the incidence of new myocardial infarction or stroke in persons without clinical cardiovascular disease. METHODS Noninvasive measurements of the intima and media...

OBJECTIVE To determine site specific carotid intima-media thickness: common-carotid artery and carotid bifurcation in hypercholesterolemia patients as a marker for atherosclerosis. METHODS Fifty patients with hypercholesterolemia and twenty controls were selected after getting informed consent regarding the investigation of carotid- intima media thickness by B-mode ultrasound. All the patient...