OBJECTIVE To evaluate a stepped-dose protocol for intralesional injection of cidofovir in children with recurrent respiratory papillomatosis (RRP). DESIGN Prospective, nonrandomized case series. SETTING Tertiary care children's hospital. PARTICIPANTS Eleven children undergoing evaluation for RRP from June 1, 2000, through December 31, 2001. INTERVENTION Intralesional injection of cidofo...

PURPOSE To report the patient characteristics and treatment outcomes in 12 cases of orbital lymphangioma. METHODS In this study, orbital lymphangioma was diagnosed based on clinical, radiologic (computed tomography, magnetic resonance imaging), and histologic findings when possible. Patients whose vision was not compromised by orbital lymphangioma, or that did not have increased intraocular p...

The pretibial myxedema is a manifestation of Graves' disease characterized by accumulation of glycosaminoglycans in the reticular dermis. The dermopathy is self-limiting but in some cases may cause cosmetic and functional damage. Conventional treatment is use of topical steroids under occlusive dressing, however the intralesional application has shown good results. We present a case of pretibia...

application in photodynamic therapy (PDT). The authors did not mention intralesional PDT, a seldom used technique which potential, though, is in our opinion underrecognized and underestimated. As shown in table 1 , intralesional PDT has been reported to be an effective and safe treatment for skin metastases of breast cancer [2] , superficial and nodular basal-cell carcinoma [3, 4, 6, 7] , squam...

Periorbital hemangioma may lead to the vision impairment so effective treatment should be adopted in time. In this study, we made a retrospective analysis of intralesional glucocorticoids and systemic propranolol in the management of periorbital hemangioma. From Jan. 2006 to Dec. 2013, twenty-five children with periorbital hemangioma were enrolled into this study. Among them, sixteen children a...

Ultrasound-guided intralesional injection of mesenchymal stem cells (MSCs) is held as the benchmark for cell delivery in tendonitis. The primary objective of this study was to investigate the immediate cell distribution following intralesional injection of MSCs. Unilateral superficial digital flexor tendon (SDFT) lesions were created in the forelimb of six horses and injected with 10 × 106 MSCs...

A 7-year-old Korean girl presented with an 8-month history of an erythematous hard plaque on her left hand. There was no history of trauma. On physical examination, a 1.4 0.8-cm firm plaque was observed on the ulnar surface of the left hand at the metacarpophalangeal level (Figure). Histopathologic examination showed moderately cellular fibroblasts throughout the dermis. Hematoxylineosin staini...