نتایج جستجو برای: intraperitoneal injection

تعداد نتایج: 168232  

Journal: :The Journal of Experimental Medicine 1976
M Cancro M Potter

The intraperitoneal injection of pristane (2,6,10,14-tetramethylpentadecane) produces an environment conductive to primary plasmacytoma growth in as few as 3 days. After pristane injection, the total free peritoneal cell population increases from a normal value of 1.55 X 10(6) to 5.28 X 10(6) and remains at this elevated level for at least 50 days. The adherent peritoneal cell population, compo...

Journal: :The Journal of Experimental Medicine 1994
K Matsuura T Ishida M Setoguchi Y Higuchi S Akizuki S Yamamoto

Western blot analysis showed that a monoclonal antibody against recombinant mouse CD14 (mCD14), designated rmC5-3, specifically reacted with mouse macrophage cell line J774, but not myeloma cell line NS1. Fluorographic and immunocytochemical analysis demonstrated specific binding of rmC5-3 with mouse resident macrophages, inflammatory monocytes and neutrophils, and macrophage cell lines. Immuno...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1983
K R Patel M P Li J D Baldeschwieler

The effect of dextran sulfate (DS, 500,000 Mr) and multilamellar vesicles (MLV) as liver blockade agents has been investigated in mice. Intravenous injection of unlabeled MLV prior to radioactive MLV caused moderate reduction in the liver uptake and increased tibia, lung, and spleen uptake. More drastic differences were observed with intraperitoneal injection of DS. When tested in the range of ...

Journal: :American journal of physiology. Endocrinology and metabolism 2016
Sheng-Ping Wang Dan Zhou Zuliang Yao Santhosh Satapati Ying Chen Natalie A Daurio Aleksandr Petrov Xiaolan Shen Daniel Metzger Wu Yin Andrea R Nawrocki George J Eiermann Joyce Hwa Craig Fancourt Corin Miller Kithsiri Herath Thomas P Roddy Deborah Slipetz Mark D Erion Stephen F Previs David E Kelley

Aberrant regulation of glucose production makes a critical contribution to the impaired glycemic control that is observed in type 2 diabetes. Although isotopic tracer methods have proven to be informative in quantifying the magnitude of such alterations, it is presumed that one must rely on venous access to administer glucose tracers which therein presents obstacles for the routine application ...

2017
Nizar Khatib Zeev Weiner Yuval Ginsberg Nibal Awad Ron Beloosesky

OBJECTIVE Increased inflammatory response may be associated with adverse clinical outcomes, especially in the neonatal period. The aims of this study were to determine whether N-acetyl-cysteine (NAC), an anti-inflammatory agent, attenuates the inflammatory response in young rats and to determine the most effective route of administration. METHODS Four groups of Sprague-Dawley rats (in each gr...

Journal: :JOP : Journal of the pancreas 2009
Cavit Cöl Kahraman Dinler Ahmet Oguz Hasdemir Guler Bugdayci

CONTEXT Several experimental studies have been carried out to explain the physiopathological mechanisms and to introduce endocrinological, enzymatic, biochemical and histopathological changes in organisms during acute pancreatitis. OBJECTIVE To evaluate the effect of an intraperitoneal injection of melatonin on serum amylase levels. DESIGN Experimental acute pancreatitis was experimentally ...

2014
HUABO CAI LUYA LIAN YU WANG YUANYUAN YU WEI LIU

The aim of this study was to explore the protective effects of Salvia miltiorrhiza injection against learning and memory impairment in streptozotocin (STZ)-induced diabetic rats and the possible mechanism involved. Sprague Dawley male rats (n=30) were randomized into three groups: Diabetes, diabetes treated with S. miltiorrhiza injection and normal control. Diabetes was induced by an intraperit...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2001
L E Goehler R P Gaykema M K Hansen J L Kleiner S F Maier L R Watkins

The paraventricular nucleus of the hypothalamus (PVH) occupies a pivotal point within the network of brain nuclei coordinating critical host-defense responses. In mice, T cell-dependent immune stimuli, including the bacterial superantigen staphylococcal enterotoxin B (SEB), can activate the PVH. To determine whether T cell-dependent immune stimuli activate the PVH in rats, we assessed plasma co...

Journal: :Acta neurobiologiae experimentalis 1976
W Buczko

A mixture of fibrinopeptides A and B did not evoke any significant central effects when given by intraperitoneal injection, whereas it increased psychomotor activity when injected into a cerebral ventricle. The fibrinopeptides when given by intraperitoneal injection interacted with amphetamine to increase locomotor activity and with chlorpromazine to decrease both locomotor activity and body te...

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