AIMS To understand public and general practitioner (GP) opinion on the acceptability of randomized policy design (RPD) studies (cluster randomized trials) of prescription medicines in Scotland. METHODS We surveyed public opinion on the concept of RPD studies in a sample of 1040 adults to determine acceptability and understand how people feel when changes are made to their medicines. We also s...

Introduction: Fluorine (F) magnetic resonance spectroscopy (MRS) can monitor the concentration and metabolism of fluorinated cancer drugs like 5-fluorouracil (5-FU) and its oral prodrug capecitabine in vivo [1]. Previous F MRS animal studies of capecitabine and 5-FU metabolism used a variety of anesthetic agents including injectable fluorinated compounds like Hypnovel and Hypnorm [2]. Fluorinat...

Refractory status epilepticus (RSE) is an important and serious clinical problem that typically requires prolonged and high-level intensive care, and is often associated with poor outcome. This review addresses some of the current issues concerning the management of RSE, including recent definitions used for clinical studies, epidemiology, clinical course, and outcome. Current approaches to tre...

BACKGROUND The aim of this study was to investigate the analgesic effects of intravenous flurbiprofen axetil for the refractory pain in cancer patients. METHODS 2109 patients were screened from the department of medical oncology, the first affiliated hospital of Anhui medical university in China between October of 2007 and October of 2008. Thirty-seven cases of cancer patients who had bad eff...

Introduction These days, the need for more information and familiarity with inflammatory response to different anesthetic drugs increase. Not only some patients suffering from immune reactions against drugs, but all surgical are liable decrease in immunity postoperatively. This may increase postoperative morbidity mortality, affects healing, spread of tumors is due surgery trauma causing imbala...

The social functions of urbanized areas are highly dependent on and supported by the convenient access to public transportation systems, particularly for the less privileged populations who have restrained auto ownership. To accurately evaluate the public transit accessibility, it is critical to capture the spatiotemporal variation of transit services. This can be achieved by measuring the shor...

In recent years there has been increasing concern about the identi…cation of parameters in dynamic stochastic general equilibrium (DSGE) models. Given the structure of DSGE models it may be di¢ cult to determine whether a parameter is identi…ed. For the researcher using Bayesian methods, a lack of identi…cation may not be evident since the posterior of a parameter of interest may di¤er from its...

Gastrointestinal endoscopy (GIE) is a procedure for diagnosis and treatment of gastrointestinal tract abnormalities. This procedure requires some forms of anesthe‐ sia. The goal of procedural anesthesia is safe, effective control of pain and anxiety, as well as an appropriate degree of memory loss or reduced awareness. Generally, the majority of GIE procedures are performed by using topical ane...

Introduction For decades thiobarbiturates have been used to induce and maintain short term (15 30 minutes) general anesthesia in equids. Thiamylal is no longer commercially available, at least in the United States, but use of thiopental remains widespread. In earlier years these ultrashort acting barbiturates were the agents of choice to induce short term recumbency in tranquilized horses. Late...

Objective: To compare and analyze the effect safety of double tube laryngeal mask endotracheal intubation general anesthesia in fast track for limb orthopaedic surgery children with cerebral palsy. Methods: 78 palsy undergoing orthopedic were randomly divided into group group, 39 cases each group. The perioperative hemodynamic indexes, related complications or adverse reaction rates two groups ...