Kawasaki disease is an acute febrile condition seen in children. However, it is also well recognized that some patients do not fulfill the classic diagnostic criteria for the diagnosis of kawasaki disease. The incomplete form of kawasaki disease is termed as 'Incomplete KD' or 'Atypical KD'. We present a case of a 6 year old child with a history of prolonged fever, periorbital, oral and lip cha...

The Authors Reply: Both these letters ask whether there could be different interpretations of our results. In response to Thomas et al.: we first want to stress that we never claimed “a causal relationship between lower rates of criminality and pharmacologic treatment for ADHD.” However, we do think that the most plausible explanation is that medication reduces the risk. Thomas et al. argue tha...

Intravenous immunization of New Zealand red rabbits with streptococcal group-specific bacterial vaccines yielded sera which possessed markedly elevated gamma-globulin. The sera of one rabbit immunized with Group A-variant vaccine possessed 55 mg/ml of gamma-globulin. The bulk of this gamma-globulin, identified as gamma(G)-globulin, was homogeneous by zone electrophoresis and of specificity dire...

Many trials have been done on steroid-resistant atopic dermatitis. Recently, intravenous immune globulin (i.v.IG) was reported to be effective in the treatment of steroid-dependent atopic dermatitis. The aim of this study was to clarify whether i.v.IG therapy is effective in steroid-resistant atopic dermatitis. Forty-one steroid-resistant atopic dermatitis patients were tested in this study. Pa...

PURPOSE A case of acute stroke in a patient who was receiving high-dose intravenous immune globulin (IVIG) for dermatomyositis is reported. SUMMARY A 43-year-old woman presented with overwhelming proximal weakness and myalgias, swelling in her hands, facial and knee rash, generalized fatigue, numbness in her left arm, and lower-back pain. Physical examination revealed that she had symptoms co...

Human immune serum globulin (HISG) therapy is the mainstay of treatment for patients with antibody immunodeficiency. Treatment with ‘y-globulin allows many of these patients to remain symptomfree for prolonged periods. Three types of human immunoglobulin are available for therapeutic use: (1) regular HISG for intramuscular (IM) use, derived from a panel of normal donors, therefore containing a ...

A small subset of patients with antiphospholipid syndrome (APS) may develop widespread thrombotic disease organ damage, referred to as catastrophic APS (CAPS) that is associated a high mortality. Medical therapy typically involves combination anticoagulation, systemic glucocorticoids, plasmapheresis, and intravenous immune globulin (IVIG). There currently no consensus for the management refract...