INTRODUCTION I therapy is a choice for Graves' hyperthyroidism. Several factors that affect the success of I treatment in Graves' disease (GD) patients have been put forward. The aim of this retrospective study was to evaluate the factors influencing the success of I therapy and the occurrence of hypothyroidism after I therapy. PATIENTS AND METHODS We reviewed 325 GD patients, who were well d...

The most common side effects of amiodarone therapy include disruptions of thyroid function with the incidence range from 14-18% [1, 2]. In fact this antiarrhythmic drug is rich in iodine and during common therapy the oversupply of iodine is 50-100 times higher than its optimal intake. Moreover, due to its intrinsic qualities (not related to iodine load), such as structural resemblance to thyroi...

Objective: The present study aimed to assess the thyroid outcomes six-months after radioactive Iodine-131 therapy (RIT) among hyperthyroid patients and identify factors associated with them.
 Methods: This retrospective observational was conducted at department of Nuclear Medicine Molecular Imaging, Northwest General Hospital & Research Centre during 2013 2019. For purpose, 153 were st...

BACKGROUND Low iodine diet (LID) is recommended in patients with differentiated thyroid cancer before radioiodine administration. Patients with increased thyroglobulin (Tg) level, but negative (131)I whole body scan present diagnostic and therapeutic dilemma. This study was designed to evaluate the benefit of a two-week LID in patients with elevated serum Tg levels and negative (131)I whole bod...

Three patients' medical history, clinical manifestation, imaging characteristic, therapy and prognosis of calvaria metastasis from follicular thyroid carcinoma (FTC) in our hospital were retrospectively analyzed by reviewing medical literature. In case one, the tumor in frontal bone and fossa orbital was total resected, no further treatment was performed, the patient gave up on therapy and died...

A method is described for the determination of serum thyroxine using ion-exchange resin sponges. The principle is based on the use of protein-binding sites and part of the technique is similar to the Triomet resin uptake test. An isotope extraction recovery procedure is incorporated in the method. Studies of factors influencing the analysis are reported and the results of tests of accuracy, pre...

Radioiodine therapy of nonthyroid cancers after sodium iodide symporter (NIS) gene delivery has been proposed as a potential application of gene therapy. However, it seems to be precluded by the rapid efflux of taken up iodine from most transduced xenografted tumors. We present an in vivo kinetic study of NIS-related hepatic iodine uptake in an aggressive model of hepatocarcinoma induced by die...

Purpose: To investigate the prognostic value of serum-stimulated thyroglobulin (ps-Tg) before first 131I therapy in patients with metastatic radioactive iodine-refractory differentiated thyroid cancer (RR-DTC). Methods: From August 2017 to 2020, clinical data for 160 papillary carcinoma (PTC) who received thyroidectomy and treatment were analyzed retrospectively. Differences related indices com...

  Introduction: Patients administered with a therapeutic dose of 131I for thyroid cancer treatment are potential sources of unacceptably high radiation exposure to other individuals, particularly the patient's immediate family members. The aim of this study is to investigate effects of early liothyronine consumption after radio-iodine therapy on accumulated dose and e...

The protective effects of iodine on breast cancer have been postulated from epidemiologic evidence and described in animal models. The molecular mechanisms responsible have not been identified but laboratory evidence suggests that iodine may inhibit cancer promotion through modulation of the estrogen pathway. To elucidate the role of iodine in breast cancer, the effect of Lugol's iodine solutio...