INTRODUCTION Achieving profound pulpal anesthesia can be difficult in patients with symptomatic irreversible pulpitis. This study provides a systematic review and meta-analysis to address the population, intervention, comparison, outcome (PICO) question: in adults with symptomatic irreversible pulpitis who are undergoing endodontic treatment, what is the comparative efficacy of articaine compar...

introduction: the aim of this randomized-controlled clinical trial was to assess the effect of intraligamentary (pdl) injection of dexamethasone on onset and severity of post-treatment pain in patients with symptomatic irreversible pulpitis. methods and materials: a total number of 60 volunteers were included according to the inclusion criteria and were assigned to three groups ( n =20). after ...

introduction: the aim of the present study was to compare the effect of two different rotary instruments on postoperative pain in teeth with asymptomatic irreversible pulpitis. methods and materials: a total of 78 mandibular first and second molars were divided into two groups ( n =39) and their root canal preparation was carried out with either race or protaper rotary instruments. all the subj...

introduction: post-endodontic pain is one of the main problems for both patients and dentists. the purpose of this study was to compare the effectiveness of premedication with indomethacin and ibuprofen for management of postoperative endodontic pain. methods and materials: in this clinical trial, mandibular molars with irreversible pulpitis were endodontically treated in 66 patients. the medic...

Attaining local anesthesia for the treatment of teeth diagnosed with irreversible pulpitis ("hot" tooth) can be a challenge. This article looks at the strategies a dentist can use to help achieve adequate pulpal anesthesia for the patient, thereby eliminating or reducing treatment pain.

e l b c t p p c p bstract he Cochrane Systematic Review promotes evidenceased outcomes studies. The review summarized here as conducted in an attempt to achieve reliable evience concerning the effectiveness, or otherwise, of rescribing antibiotics for patients having irreversible ulpitis. A competent search strategy was developed nd used across several databases including MEDLINE o identify ran...

Pulpal disease, specifically dental pulpitis, is triggered by exogeneous stimuli from cariogenic bacteria or traumatic injury. The specific host defense in the dental pulp is regulated by the innate and adaptive immunity, of which the pulp-dentin complex odontoblasts play an essential role in the early stage of the dental immune response. It has been reported that the NLRP3 inflammasome is expr...