نتایج جستجو برای: isocoumarin
تعداد نتایج: 145 فیلتر نتایج به سال:
Two new phenolic glycosides (1 and 2) and two new isocoumarin glycosides (3 and 4), along with 14 known compounds (5-18), were isolated from the stems of Homalium paniculiflorum. Their structures were established on the basis of extensive spectroscopic analyses and chemical methods. All new compounds were evaluated for their anti-inflammatory activities via examining the inhibitory activity on ...
The total synthesis of the human telomerase inhibitor γ-rubromycin in its racemic form was accomplished in 3.8 % overall yield. The key feature of this synthesis is an efficient acid-catalyzed spiroketalization for the construction of the spiroketal core. The required electronically well-balanced spiroketal precursor was obtained by the convergent assembly of a naphthyl-substituted aldehyde, an...
Aspyran (1), a novel compound, and the known isocoumarin asperentin (2), also known as cladosporin, together with its analogues 3-6 were isolated from Aspergillus sp. and their structures established by spectroscopic methods including 2D NMR spectroscopy. The effects of 1-6 on plant growth were examined by bioassays using lettuce and rice seedlings. Compounds 1 and 3 promoted the root growth of...
In the continuation of our study substituted isocoumarins a series novel 3-azolyl isocoumarin and their thio derivatives, including some related lactone compounds was prepared biologically profiled against C. albicans showing moderate activity with MIC values in range 4?60 ?g mL-1, general. The additional characterisation selected carried out by exploring on CYP3A4 CYP2D6 enzymes, while experim...
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