Different external stimuli are perceived by multiple sensor histidine kinases and transmitted phosphorylation via the phosphotransfer protein Ypd1p in multistep phosphorelay system of high osmolarity glycerol signaling pathway filamentous fungi. How signal propagation takes place is still not known detail since kinase genes most fungi coded genome, whereas only one gene for exists. That raises ...

induced resistance to pathogen is one of the ways which plants use against biotic stresses. pathogenesis-related proteins(pr), including chitinase and β-1,3-glucanase synthesized by the plant in response to pathogenic infection. in this investigation, the expression of two isoforms: acidic and basic of chitinase and β-1,3-glucanasegenes were analyzed at 0, 6, 12, 24, 48 and 72 hours after funga...

lipoprotein (a) [lp (a) is formed by assembly of ldl-particles and the carbohydrate rich protein, apolipoprotein (a) [apo (a)]. elevated plasma lp (a) levels are an independent predictor of the development of premature coronary artery disease (cad), but is not clear whether the apo (a) isoform plays on additional and independent role or not. to investigate the possible effect of apo (a) isoform...

The objective of this descriptive study was to determine Felis domesticus (cat) and Canis familiaris (dog) protein epitopes that bind strongly to selected HLA class II alleles to identify synthetic vaccine candidate epitopes and to identify individuals/populations who are likely to respond to vaccines. FASTA amino acid sequences of experimentally validated allergenic proteins of house cat and d...

Background: Promyelocytic leukemia protein (PML) is a tumor suppressor protein that is involved in myeloid cell differentiation in response to retinoic acid (RA). In addition, RA acts as a natural morphogen in neural development. Objectives: This study aimed to examine PML gene expression in different stages of in vitro neural differentiation of NT2 cells, and to investigate the possible role o...

The main objective of this study was to analyze by real-time quantitative polymerase chain reaction (RT-qPCR) the expression patterns myosin heavy (MHC) isoforms (MHC-I, MHC-IIa, MHC-IIx) in sphenomandibularis portion temporalis muscle. We expected find differences between and other portions that could be related functional characteristics identified electromyography. dissected right muscle ten...

Vitamin E, a generic term for tocopherol (T) and tocotrienol (T3), is one of the most potent lipid-soluble antioxidants in body. It classified into T T3 based on difference side chain structure. have four isoforms: ?-, ?-, ?-, ?, which different chroman rings. Both exhibit similar ability to scavenge free radicals, extent this depends However, they display unique cytoprotective activities cultu...

the effects of fish weight on salinity tolerance were studied in caspian salmon (salmo trutta caspius) parr. 180 fish (all with 2 years old but with three weights; 5, 15, 25g) were selected and they reared in freshwater (fw) and brackish water (bw; 13ppt salinity) for 10 days. the mrna expression of two α-subunit isoforms of na+, k+-atpase (α1a and α1b) and nkcc co-transporters were studied in ...

The transcription of mammalian genomes exhibits an intriguing complexity and numerous novel RNA molecules have been identified. Viruses with large DNA genomes, especially herpesviruses, generate many different species, including long non-coding RNAs (lncRNAs). Dense viral can multigenic transcripts in addition to commonly observed antisense transcripts. It is essential study the biological role...

In this work, two classes of Carbonic Anhydrase (CA) inhibitors, sulfonamide and coumarin derivatives linked to pyta moiety (2a-b) their corresponding rhenium complexes (3a-b), were designed. These compounds synthesized fully characterized by classical analytical methods X-ray diffraction. All the evaluated for inhibitory activity against hCA isoforms I, II, IX XII. They exhibited high activiti...