OBJECTIVE The presence of hematuria has been suggested to indicate nondiabetic nephropathy in diabetic patients with proteinuria. However, hematuria is frequently found in patients with biopsy-proven diabetic glomerulosclerosis without nondiabetic nephropathy. Urine microscopy allows discrimination of glomerular hematuria, which is defined as acanthocyturia (urinary excretion of acanthocytes, w...

We describe a case of a 12-year-old boy with an isolated macroscopic hematuria. A urinary ultrasound revealed a bladder tumor next to the right ureteric orifice. A biopsy revealed a urothelial papilloma. He underwent a successful resection by cystostomy. This benign tumor is extremely rare in children and its management remains controversial. 2016 The Authors. Published by Elsevier Inc. This is...

BACKGROUND Percutaneous renal biopsy (PRB) is essential for the diagnosis, prognosis, and management of children with unknown kidney disease. In this study, the safety and efficacy of PRB is investigated, and also the common etiologies of childhood kidney disease, based on histological findings. In addition, we explored the role of PRBs in the diagnosis of children who presented with persistent...

Hematuria is one of the most common conditions confronting clinical urologists and is present in many genitourinary pathology conditions. Although researchers have studied hematuria symptoms in an effort to determine the best diagnostic pathway, the existing lack of scientific evidence has created variations in clinical practice. The literature does not provide enough evidence to significantly ...

The identification of hematuria or proteinuria in an otherwise healthy child can cause anxiety to both the family and the pediatrician. The etiology of hematuria and proteinuria includes a long list of conditions, and detailed workup can be exhaustive, expensive and not essential in most of the patients. As will be described in this paper, most of the children with proteinuria or hematuria have...

The detection of microscopic hematuria in a child's urine prompts evaluation for renal and urinary bladder causes. Microscopic hematuria identified during a routine physical examination by the pediatrician is much more common than macroscopic hematuria. Persistent microscopic hematuria is particularly worrisome and may require a percutaneous needle core kidney biopsy to determine whether the et...

BACKGROUND The presence of blood in the urine, or hematuria, is a common finding in clinical practice and can sometimes be a sign of occult cancer. This article describes the clinical epidemiology of hematuria and the current state of practice and science in this context and provides suggestions for clinicians evaluating patients with hematuria. METHODS A narrative review of available clinica...

amyloidosis is a disorder of protein metabolism characterized by extracellular deposition of abnormal protein fibrils. it may either be localized to any organ or systematically distributed throughout the body. the biochemical nature of proteins varies but the physical and tinctorial properties are shared by all the amyloidogenic proteins. in the west, it is mainly composed of amyloid light (al)...