AIM This study examines the association between childhood physical abuse (CPA) and sexual abuse (CSA) and the development of cannabis abuse and dependence among adolescents and young adults while controlling for genetic and environmental risk factors. DESIGN To control for familial risk differences related to paternal drug dependence that might confound the relationship between CSA and CPA an...

BACKGROUND Studies of the prevalence of DSM-IV alcohol use disorders (AUDs) in general population samples of adolescents and adults are rare. Comparisons of the prevalence of alcohol abuse and dependence in adolescent surveys with the prevalence in adult general population surveys are confounded by differences in survey design and measurement, thereby reducing their validity. The purpose of the...

conclusions multiple prescription drug abuse and salt/salty food addiction usually reflects a personality of addiction, which leads to harmful use and dependence. case presentation a 28-year-old woman presented with tetany due to hypocalcemia, hypokalemia and hypomagnesemia. she had a history of laxative and diuretic abuse, and salt craving. psychiatric evaluation revealed a disturbed social hi...

background: military service is a crucial period in the lives of young people and during this period soldier facing with multiple psychosocial problems. objectives: the present study aimed to explore structural analysis of the relationships between depression, drug abuse, social support and the risk of suicidal ideation among military medical university soldiers in iran. methods: in the present...

background: given the high prevalence of addiction in iran and its social and health problems, addiction is considered as one of the few national health priority. this study compared the views of addicts and their families about the causes of drug abuse that referred to addiction centers in khorramabad, iran. methods: this cross-sectional study was conducted on addicts and their families who re...

AIMS Although previous twin studies have modeled the association between drug initiation and abuse, none has included the obvious risk factor of drug availability. Our aim is to determine whether the genetic and environmental risk factors for cannabis availability also generate variation in cannabis initiation and/or progression to DSM-IV symptoms of abuse. DESIGN We used multi-stage modeling...

BACKGROUND Violent victimisation among people with major mental illness is well-documented but the risk factors for criminal violent victimisation are not well understood. METHODS We examined the relationship between illness-related variables, indices of substance abuse and previous history of violence in a sample of 23 male criminally violently victimized and 69 non-criminally violently vict...

Triple reuptake inhibitors (TRIs) that block the dopamine transporter (DAT), norepinephrine transporter, and serotonin transporter are being developed as a new class of antidepressant that may have better efficacy and fewer side effects compared with traditional antidepressants. We describe a novel TRI, 2-[4-(4-chlorophenyl)-1-methylpiperidin-3-ylmethylsulfanyl]-1-(3-methylpiperidin-1-yl)-ethan...

800x600 background : hepatitis b and c infections have remained major global health burdens during the most recent century. the viral agents responsible for these diseases share common modes of transmission with human immunodeficiency virus (hiv) such as needle-sharing in iv drug abusers. coinfection of hepatitis b or c with hiv increases the rate of progression of chronic liver disease. given ...

objective: the present study aimed to determine the frequency of drug abused in a sample of university students in rafsanjan, iran. methods: in this cross-sectional study, 1,260 students volunteered (311 males and 949 females) with mean age of 21.35 years. data were collected by a self-administrated questionnaire regarding drugs abuse and demographic information. results: benzodiazepines were t...