Introduction Medication errors represent a serious issue affecting the U.S. health care system, accounting for the largest category of patient safety incidents within the larger category of medical errors. One report estimated that at least 1.5 million preventable medication errors occur in the U.S. each year. A list of high-alert medications (those with the highest potential for patient harm i...

Abstract Background A tracheo-innominate fistula is a rare but life-threatening complication of tracheostomy and has mortality rate 100% without therapy. The underlying cause an acquired between the brachiocephalic trunk trachea, induced by cannula’s mechanical impact. Case presentation 25-year-old female was admitted with pulsatile bleeding from tracheostomy. artery fistula, which difficult to...

This study exatnined patterns of psychotropic medication use among 120 participants with intellectual disabilities (ID) who used to live in facilities and now reside in community-based settings in Ontario. There were significantly more participants taking psychotropic medication in the community (83.30/0) than in the facility (74.2%). Of those who showed change, 4.2% were taking medication in t...

BACKGROUND Intravenous (IV), intramuscular (IM), and subcutaneous (SC) are the three most frequently used injection routes in medication administration. Comparative studies of SC versus IV, IM versus IV, or IM versus SC have been sporadically conducted, and some new findings are completely different from the dosage recommendation as described in prescribing information. However, clinicians may ...

BACKGROUND Severe depression can be a life-threatening disorder, especially in elderly patients. A fast-acting treatment is crucial for this group. Electroconvulsive therapy (ECT) may work faster than medication. AIMS To compare the speed of remission using ECT v. medication in elderly in-patients. METHOD The speed of remission in in-patients with a DSM-IV diagnosis of major depression (bas...

Intravenous (IV) medications are vital in the management of hospitalized patients. Inpatients frequently receive several IV medications concurrently, and these are commonly delivered with infusion pump systems. In particular, critically ill patients receive potent "high-alert" IV drugs, many with narrow safety margins requiring careful nursing titration. However, while intravenous medications h...

the present work describes the studies on the coordination behaviour of 4[n-(benzalidene) amino]antipyrine semicarbazone (baaps) (i), 4[n-(furfural)amino]antipyrine semicarbazone (ffaaps) (ii) and 4[n-(cinnamalidene)amino]antipyrine semicarbazone (caaps) (iii) in presence of dimethyl sulfoxide (dmso) or diphenyl sulfoxide (dpso) towards th4+ and uo22+ salts. all the complexes were isolated in n...

Adherence is a potentially significant issue in oral therapy for breast cancer. Suboptimal adherence to medication regimens impacts clinical benefit and can result in treatment resistance, disease progression, and even death. Nonadherence is a greater issue with oral medications because the majority of responsibility shifts from healthcare professionals to the patient. Improving adherence to me...

Disclosure: The authors are employees of CareFusion, which holds many patents, including those associated with clinical device operating parameters. They also were employed by the predecessor companies that were involved in developing modular smart intravenous (IV) infusion safety systems and the associated wireless connectivity. This article reports their firsthand experience of what it took, ...

Overdose of cardiovascular medications such as beta blockers and calcium channel blockers cause impaired cardiac contractility, vasoplegia, and/or rhythm disturbances. In addition to conventional management of limiting absorption, increasing elimination and hemodynamic support intravenous (IV) calcium infusion, hyperinsulinemia-euglycemia therapy, glucagon infusion, and IV lipid emulsion have b...