BACKGROUND Interventricular hemorrhage (IVH) and Broncho pulmonary dysplasia(BPD) commonly occur in premature infants and they associate with platelet dysfunction. The aim of this study was to investigate the association of MPV and occurrence of IVH and BPD. MATERIALS AND METHODS In this cross sectional study, 3 groups including IVH, BPD and control were compared. All participants were preter...

Intraventricular hemorrhage (IVH) secondary to spontaneous intracerebral hemorrhage (ICH) results in death in 32% to 43% of cases and poor functional outcome in most survivors. In severe IVH with obstruction of the third or fourth ventricle, the placement of an extraventricular drain can help lower raised intracranial pressure. Meta-analysis shows this reduces mortality, but poor outcomes remai...

BACKGROUND Pathogenesis of intraventricular hemorrhage (IVH) in premature infants is multifactorial. Little is known about the impact of genetic variants in the vitamin K-dependent coagulation system on the development of IVH. METHODS Polymorphisms in the genes encoding vitamin K epoxide reductase complex 1 (VKORC1 -1639G>A) and coagulation factor 7 (F7 -323Ins10) were examined prospectively ...

BACKGROUND AND PURPOSE In the treatment of severe intraventricular hemorrhage (IVH), thrombolytic use and clot size are known to influence clot lysis rates. We evaluated the effect of other variables on IVH clot lysis rates among patients treated with recombinant tissue-type plasminogen activator or placebo. METHODS One hundred patients with IVH and intracerebral hemorrhage volume <30 mL requ...

Introduction: Intraventricular Haemorrhage is the most common forms of brain injury in preterm neonates1, more commonly seen smallest and neonates contributing to mortality, morbidity during time stay hospital. IVH among VLBW with incidence around 20-25% out which 2/3rd are mild moderate severity [grade 1-2]. Objective: To study intraventricular hemorrhage neonates. Methods: This a hospital bas...

BACKGROUND Intraventricular hemorrhage (IVH) is a major cause of neurologic disabilities in preterm newborns. We evaluated the use of plasma activin A concentrations to predict the development of perinatal IVH. METHODS We measured nucleated erythrocyte (NRBC) counts, plasma activin A, hypoxanthine (Hyp), and xanthine (Xan) in arterial blood samples obtained from 53 preterm infants during the ...

background interventricular hemorrhage (ivh) and broncho pulmonary dysplasia(bpd) commonly occur in premature infants and they associate with platelet dysfunction. the aim of this study was to investigate the association of mpv and occurrence of ivh and bpd. materials and methods in this cross sectional study, 3 groups including ivh, bpd and control were compared. all participants were preterm ...

BACKGROUND Infants with severe intraventricular-periventricular hemorrhage (IVH) have higher absolute nucleated red blood cell counts (aNRBC) at birth (a marker of intrauterine hypoxia) than controls. Periventricular leukomalacia (PVL) is known to be associated with prenatal and postnatal events. Whether PVL is also linked to intrauterine hypoxia is unknown. OBJECTIVES To test the hypothesis ...

Background: Intraventricular hemorrhage (IVH) in preterm neonates is a serious problem in neonatal intensive care units (NICU) worldwide. IVH is reported in approximately 60-70% of very-low-birth-weight (VLBW) neonates. The present study aimed to assess the association of IVH with neonatal characteristics and serum markers, such as serum Interleukin-6 (IL-6) level, in preterm neonates in an aca...

PURPOSE This study aimed to assess early development in very low birth weight (VLBW) infants with mild intraventricular hemorrhage (IVH) or those without IVH and to identify the perinatal morbidities affecting early neurodevelopmental outcome. METHODS Bayley Scales of Infant Development-II was used for assessing neurological development in 49 infants with a birth weight <1,500 g and with low ...