Abnormal joint morphogenesis is linked to clinical conditions such as Developmental Dysplasia of the Hip (DDH) and to osteoarthritis (OA). Muscle activity is known to be important during the developmental process of joint morphogenesis. However, less is known about how this mechanical stimulus affects the behaviour of joint cells to generate altered morphology. Using zebrafish, in which we can ...

temporomandibular joint (tmj) diseases and disorders refer to a complex and poorly understood set of conditions, manifested by pain in the area of the jaw and associated muscles and limitations in the ability to make the normal movements of speech, facial expression, eating, chewing, and swallowing. the conventional soft occlusal splint therapy is a much safer and effective mode of a conservati...

We applied information-theoretic methods to multi-electrode array recordings in the primary visual cortex of cats to quantify the cooperation and temporal structure that arises in the responses to drifting sinusoid gratings. When testing small differences in orientation (<10o), the temporal structure and joint firing can contribute information for discriminating responses. The contributions fro...

In general, the orientation interpolation of industrial robots has been done based on Euler angle system which can result in singular point (so-called Gimbal Lock). However, quaternion interpolation has the advantage of natural (specifically smooth) orientation interpolation without Gimbal Lock. This paper presents the application of quaternion interpolation, specifically Spherical Linear IntER...

AIM To analyze how various implants placement variables affect sacroiliac (SI) joint range of motion. METHODS An experimentally validated finite element model of the lumbar spine and pelvis was used to simulate a fusion of the SI joint using various placement configurations of triangular implants (iFuse Implant System®). Placement configurations were varied by changing implant orientation, su...

How to satisfactorily implement the public–private partnership (PPP) network is most important target for infrastructure and public services policymakers. In this article, we elaborate on how project- process-management styles can combine deliver a satisfactory PPP. This paper uses fuzzy-set qualitative comparative analysis investigate relationship between management PPP outcomes. Specifically,...

This article presents a novel parallel spherical mechanism called Argos with three rotational degrees of freedom. Design aspects of the first prototype built of the Argos mechanism are discussed. The direct kinematic problem is solved, leading always to four nonsingular configurations of the end effector for a given set of joint angles. The inverse-kinematic problem yields two possible configur...

We study the problem of fitting a two-joint orthogonal polygonal chain to a set S of n points in the plane, where the objective function is to minimize the maximum orthogonal distance from S to the chain. We show that this problem can be solved in Θ(n) time if the orientation of the chain is fixed, and in Θ(n log n) time when the orientation is not a priori known. We also consider some variatio...

this study aims at presenting a numerical model for predicting grout flow and penetration length into the jointed rock mass using universal distinct element code (udec). the numerical model is validated using practical data and analytical method for grouting process. input data for the modeling, including geomechanical parameters along with grout properties, were obtained from a case study. the...