Report of Cases. Case 1. A 9-yearold white girl underwent excision of a small, rapidly growing, black pigmented lesion of the inferior palpebral conjunctiva and the adjacent margin of the right lower eyelid. The original histopathologic diagnosis was an active junctional nevus of the conjunctiva and eyelid margin. The lesion recurred 3 years later and was excised by a dermatologist who did not ...

Papillomatous Compound Nevus An 8-year-old boy was observed for 5 years for an enlarging, pigmented lesion on his left lower lid (Fig 1). An excisional biopsy was performed and histopathology (H&E) revealed skin with keratinized, stratified squamous epithelium in a papillomatous configuration (Figs 2 and 3). The lesion had nests of densely pigmented melanocytes within the epithelium (black arro...

BACKGROUND The aim of this study was to develop and characterize standardized in vitro three-dimensional organotypic models of human junctional epithelium (JE) and sulcular epithelium (SE). METHODS Organotypic models were constructed by growing human normal gingival keratinocytes on top of collagen matrices populated with gingival fibroblasts (GF) or periodontal ligament fibroblasts (PLF). Ti...

  Abstract   Background: To evaluate proximal junctional segment changes in Adolescent Idiopathic   Scoliosis(AIS) the posterior spinal fusion and also instrumentation also and   finding of probable risk factors, were all considered in this study.   Methods: We retrospectively reviewed radiographs of 121 consecutive patients   who underwent posterior spinal fusion for AIS from T3 or below, with...

BACKGROUND The disruption of intercellular junctions in the larynx is a pathological feature of laryngopharyngeal reflux (LPR). Good experimental models are necessary to gain greater insight into the molecular mechanisms and alterations that result from abnormal exposure of the laryngeal epithelium to acid refluxate. AIMS To characterise laryngeal tissues from different species to determine t...

Report of Cases. Case 1. A 9-yearold white girl underwent excision of a small, rapidly growing, black pigmented lesion of the inferior palpebral conjunctiva and the adjacent margin of the right lower eyelid. The original histopathologic diagnosis was an active junctional nevus of the conjunctiva and eyelid margin. The lesion recurred 3 years later and was excised by a dermatologist who did not ...

In this study, we demonstrate that fluid shear stress (FSS)-induced actin cytoskeletal reorganization and junctional formation in renal epithelial cells are nearly completely opposite the corresponding changes in vascular endothelial cells (ECs) [Thi MM et al. (2004) Proc Natl Acad Sci USA 101:16483-16488]. Mouse proximal tubule cells (PTCs) were subjected to 5 h of FSS (1 dyn/cm(2)) to investi...

The cells that constitute the membranous labyrinth in the vertebrate inner ear are all derived from a single embryonic source, namely, the otocyst. The mature inner ear epithelia contain different regions with highly differentiated cells, displaying a highly specialized cytoarchitecture. The present study was designed to determine the presence of adherens-type intercellular junctions in this ti...

The distribulion of adhesive mechanisms in the normal bronchial epithelium. S. Montefort, J. Baker, W.R. Roche, S.T. Holgate. ©ERS Journals Lld 1993. Depts of *Immunopbarmacology and ••Pathology, University of Southampton, Southampton, UK. ABSTRACT: The integrity of the bronchial epithelium is dependent on various adhesion mechanisms that sen-e to bold the composite structure or the epithelium ...