Mrvar and Doreian recently defined a notion of bipartite clustering in bipartite signed graphs that gives a measure of imbalance of the signed graph, different from previous measures (the “frustration index” or “line index of balance”, l, and Davis’s clusterability). A biclustering of a bipartite signed graph is a pair (π1, π2) of partitions of the two color classes; the sets of the partitions ...

We have determined the entire sequence of the plasmid K2 from Kluyveromyces lactis which is involved in the maintenance of both killer plasmids in the cell. K2 shares many of the characteristics of the smaller killer plasmid K1: high A+T content (74.7%) and very compact genomic organization. K2 contains ten open reading frames. Some of them overlap on different strands and some on the same stra...

SAK-RGD-K2-Hir and SAK-RGD-K2-Hirul are recombinant proteins that are derivatives of r-SAK (recombinant staphylokinase). They are characterized by their fibrin-specific plasminogen activation properties and their antithrombin and antiplatelet activities. The difference between these proteins is the presence of the antithrombotic fragment (hirudin or hirulog) in the C-terminal portion of the r-S...

It has long been conjectured that the crossing numbers of links are additive under the connected sum of links. This is a difficult problem in knot theory and has been open for more than 100 years. In fact, we do not even know that Cr(K1#K2) = Cr(K1) or Cr(K1#K2) = Cr(K2) holds in general, here K1#K2 is the connected sum of K1 and K2 and Cr(K) stands for the crossing number of the link K. The be...

Let S(R) be an o-minimal structure over R, T ⊂ R k1+k2+l a closed definable set, and π1 : R k1+k2+l → R12 , π2 : R k1+k2+l → R, π3 : R k1+k2 → R2 the projection maps as depicted below.

BACKGROUND Understanding how biotoxins kill cells is of prime importance in biomedicine and the food industry. The budding yeast (S. cerevisiae) killers serve as a convenient model to study the activity of biotoxins consistently supplying with significant insights into the basic mechanisms of virus-host cell interactions and toxin entry into eukaryotic target cells. K1 and K2 toxins are active ...

The effects of vitamin K2 on apoptosis in a variety of cancer cells have been well established in previous studies. However, the apoptotic effect of vitamin K2 on bladder cancer cells has not been evaluated. The aim of this study is to examine the apoptotic activity of Vitamin K2 in bladder cancer cells and investigate the underlying mechanism. In this study, Vitamin K2 induced apoptosis in bla...

Let S(R) be an o-minimal structure over R, T ⊂ Rk1+k2+l a closed definable set, and π1 : R k1+k2+l → R12 , π2 : R k1+k2+l → R, π3 : R k1+k2 → R2 the projection maps as depicted below.