We describe fractionation of the Plasmodium falciparum genome into 14 chromosomal DNA molecules by pulsed-field gel electrophoresis. This number agrees with the number of chromosomes observed by electron microscopic visualization of kinetochores. The assignment of 25 markers to 12 of the 14 chromosomes in three cloned parasite lines demonstrates that chromosomal size variation can greatly chang...

Molecular cytogenetic reveal details of fine chromosomal structure that are useful in studies diversification, genome organization, and evolution. However, these techniques have rarely been used to describe population-level variations the tribe Meliponini. In present study, we compared karyotype, number, localization rDNA clusters distribution a repetitive DNA sequence T. spinipes from nine loc...

Cancer cells are typically characterized by complex karyotypes including both structural and numerical changes, with aneuploidy being a ubiquitous feature. It is becoming increasingly evident that aneuploidy per se can cause chromosome mis-segregation, which explains the higher rates of chromosome gain/loss observed in aneuploid cancer cells compared to normal diploid cells, a phenotype termed ...

Question: Is alpha radiation responsible for major changes in genome structure, including karyotypic change and higher ploidy? In vitro, high doses of alpha radiation yield many chromosomal changes, while low doses yield mostly point mutations. Data description: Previously published data on karyotypic variability and the incidence of polyploidy in various animal and plant species. Search method...

Determination of the chromosome base number a taxon is fundamental to understanding karyotypic variation and its implications for evolution that group. This usually requires careful evaluation cytological literature robust phylogenetic support. The family Rutaceae (x = 9 or x 18) has long been subject debate. Here, we analyzed banding pattern, rDNA sites, genome size Dictyoloma vandellianum, su...

HALE, D. W. 1986. Heterosynapsis and suppression of chiasmata within heterozygous pericentric inversions of the Sitka deer mouse. Chromosoma 94: 425-432. HALE, D. W., AND I. F. GREENBAUM. 1988. Synapsis of a chromosomal pair heterozygous for a pericentric inversion and the presence of a heterochromatic short arm. Cytogenet. Cell Genet. In press. MACEY, M., AND L. K. DIXON. 1987. Chromosomal var...