Christian Sticherling, Andrea Menafoglio, Haran Burri, Sven Reek, Jürg Fuhrer, Vincent Ganière, Marianne Zimmerli, Istvan Babotai, Firat Duru, Etienne Pruvot On behalf of the Swiss Working Group on Cardiac Pacing and Electrophysiology and Manfred Seeberger, Christoph Kindler, Reto Basciani, Andreas Vogt, Balthasar Eberle, Carlos Marcucci, Elisabeth Ecknauer, Daniel Bolliger On behalf of the Car...

B. Sulignano, S. Hofmann, F.P. Heßberger, D. Ackermann, S. Antalic, H.G. Burkhard, B. Kindler, I. Kojouharov, P. Kuusiniemi, M. Leino, B. Lommel, R. Mann, K. Nishio, A.G. Popeko, S. Saro, H.J. Schött, B. Streicher, J. Uusitalo, A.V. Yeremin GSI, Darmstadt, Germany; Comenius University, Bratislava, Slovakia; CUPP, University of Oulu, Finland, University of Jyväskylä, Jyväskylä, Finland; JAEA, To...

9-formyljulolidine was oxidized via a microwave-assisted Willgerodt-Kindler reaction to the N-piperidine or N-morpholine julolidine-9-thioamide. 9-formyl-1,1,7,7-tetramethyljulolidine gave the corresponding N-piperidine tetramethyljulolidine-9-thioamide. The thioamides were converted to the corresponding carboxamides with trifluoroacetic anhydride. The amide group directed ortho-metalation in t...

A novel betacoronavirus, human coronavirus (HCoV-EMC), has recently been detected in humans with severe respiratory disease. Further characterization of HCoV-EMC suggests that this virus is different from severe acute respiratory syndrome coronavirus (SARS-CoV) because it is able to replicate in multiple mammalian cell lines and it does not use angiotensin-converting enzyme 2 as a receptor to a...

Let G∞ = (C d m)∞ denote the graph whose set of vertices is {1, . . . ,m}d, where two distinct vertices are adjacent iff they are either equal or adjacent in Cm in each coordinate. Let G1 = (C d m)1 denote the graph on the same set of vertices in which two vertices are adjacent iff they are adjacent in one coordinate in Cm and equal in all others. Both graphs can be viewed as graphs of the d-di...

Loss-of-function mutations in the gene encoding the integrin co-activator kindlin-1 cause Kindler syndrome. We report a novel kindlin-1-deficient keratinocyte cell line derived from a Kindler syndrome patient. Despite the expression of kindlin-2, the patient's cells display several hallmarks related to reduced function of β1 integrins, including abnormal cell morphology, cell adhesion, cell spr...

The practical synthesis of important natural polyphenolic stilbenes, including resveratrol, piceatannol and oxyresveratrol, through Perkin methodology is described. Starting from 3,5-dihydoxyacetophenone (1), the common intermediate 3,5-dimethoxyphenylacetic acid (3) can be obtained via methylation and Willgerodt-Kindler reaction. Perkin condensations between (3) and substituted phenylaldehydes...