نتایج جستجو برای: klebsiella pneumoniae
تعداد نتایج: 35504 فیلتر نتایج به سال:
INTRODUCTION Polymyxins are antimicrobial agents capable of controlling carbapenemase-producing Klebsiella pneumoniae infection. METHODS We report a cluster of four patients colonized or infected by polymyxin-resistant and Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae. RESULTS Three patients were hospitalized in adjacent wards, and two were admitted to the intensive care...
Klebsiella pneumoniae is a common cause of nosocomial pneumonia. Osteopontin (OPN) is a phosphorylated glycoprotein involved in inflammatory processes, some of which is mediated by CD44. The aim of this study was to determine the role of OPN during K. pneumoniae-induced pneumonia. Wild-type (WT) and OPN knockout (KO) mice were intranasally infected with 10⁴ colony forming units of K. pneumoniae...
Background: The increasing emergence of antimicrobial resistance among gram negative bacteria especially Enterobacteriaceae has become a global problem. Klebsiella pneumoniae is an opportunistic pathogen, which recently due to causing broad spectrum of disease and antibiotic resistance has been lionized. Efflux pumps are one of the antibiotic resistance mechanisms, which were introduced in t...
Klebsiella pneumoniae-associated pathology is largely mediated by neutrophilic inflammation. In this study, we administered Klebsiella pneumoniae to experimental guinea pig groups and the ELR-CXC chemokine antagonist CXCL8(3-72), ceftazidime, and dexamethasone to different groups, respectively. After 24 h, we assessed the animal's pulmonary inflammatory levels, including gross histopathology, a...
Abstract Background and Objective: Multiple drug resistance has increased in recent years in Klebsiella pneumoniae isolates. The Integrons are mobile genetic elements that carry antibiotics resistance genes. The aim of this study was to determine antibiotic susceptibility and the prevalence of class 1, 2, and 3 integrons in clinical Klebsiella pneumoniae isolated from clinical specimens. Materi...
Molecular typing of Klebsiella species has become important for monitoring dissemination of β-lactamase-producers in hospital environments. The present study was designed to evaluate poly-trinucleotide (GTG)(5)- and rDNA intergenic transcribed spacer (ITS)-PCR fingerprint analysis for typing of Klebsiella pneumoniae and Klebsiella oxytoca isolates. Multiple displacement amplified DNA derived fr...
Antimicrobial Susceptibility Pattern and Mutations of Outer Membrane Porin in Clinical Isolates Klebsiella pneumoniae
Phenotypic and Genotypic Investigation of Metallobetallactamase Resistance in Clinical Isolates Escherichia Coli Klebsiella Pneumoniae
Background and Objective: According to the high incidence of Klebsiella pneumoniae nosocomial infections in different wards of health care units and the emergence of high levels of antibiotic resistance, evaluating the frequency of multi-drug resistant strains and recognizing the virulence factors may help treat the related infections. Materials and Methods: In this descriptive cross-sectional...
Background and Objective: Klebsiella pneumoniae is known as one of the opportunistic pathogens. The prevalence of antibiotic resistance, emergence of multidrug resistant strains, and multiple virulence factors contribute to the development of various infections. In this regard, the aim of this study was to evaluate the frequency of fimH, magA, and rmpA genes among Klebsiella pneumoniae isolates...
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