CAMRA (Center for Advancing Microbial Risk Assessment) gathers a community of scientists that investigate several stages in the life cycle of biological agents of concern. This paper describes the knowledge management (KM) approach adopted for CAMRA’s community of scientists. The approach includes knowledge facilitators, a weband repository-based KM system, and use-centered design. The approach...

Hydroxypyruvate reductase was purified to homogeneity from the facultative methylotroph Methylobacterium extorquens AM1. It has a molecular mass of about 71 kDa, and it consists of two identical subunits with a molecular mass of about 37 kDa. This enzyme uses both NADH (Km = 0.04 mM) and NADPH (Km = 0.06 mM) as cofactors, uses hydroxypyruvate (Km = 0.1 mM) and glyoxylate (Km = 1.5 mM) as the on...

BACKGROUND As physical activity levels decrease as children age, sustainable and accessible forms of physical activity are needed from a young age. Transportation cycling is one such physical activity and has been associated with many benefits. The aims of the study were to identify whether manipulating micro-environmental factors (e.g. speed limits, evenness of cycle path) within a photographe...

PURPOSE This study examined the determinants of pacing strategy and performance during self-paced maximal exercise. METHODS Eight well-trained cyclists completed two 20-km time trials. Power output, rating of perceived exertion (RPE), positive and negative affect, and iEMG activity of the active musculature were recorded every 0.5 km, confidence in achieving preexercise goals was assessed eve...

The Mycobacterium tuberculosis ahpC gene, encoding the mycobacterial orthologue of alkylhydroperoxide reductase, undergoes an unusual regulatory cycle. The levels of AhpC alternate between stages of expression silencing in virulent strains grown as aerated cultures, secondary to a natural loss of the regulatory oxyR function in all strains of the tubercle bacillus, and expression activation in ...

Purpose – Many terms commonly used in the field of knowledge management (KM) have multiple uses and sometimes conflicting definitions because they are adapted from other research streams. Discussions of the various hierarchies of data, information, knowledge, and other related terms, although of value, are limited in providing support for KM. The purpose of this this paper is to define a new se...

BACKGROUND The purpose of this study was to examine the efficacy of introducing a fish protein hydrolysate (PEP) concurrently with carbohydrate (CHO) and whey protein (PRO) on endurance exercise metabolism and performance. METHODS In a randomised, double blind crossover design, 12 male volunteers completed an initial familiarisation followed by three experimental trials. The trials consisted ...

OBJECTIVE To report a case of exertional hyponatraemic encephalopathy that occurred despite a modest rate of fluid intake during a 109 km cycling race. METHODS Men and women cyclists were weighed before and after the race. All subjects were interviewed and their water bottles measured to quantify fluid ingestion. A blood sample was drawn after the race for the measurement of serum Na(+) conce...

Cross-spectral analysis of repeat satellite altimeter profiles was performed to compare the along-track resolution capabilities of Geosat, ERS 1 and TOPEX data. Geophysical Data Records were edited, differentiated, low-pass-filtered, and resampled at 5 Hz. All available data were then loaded into three-dimensional files where repeat cycles were aligned along-track (62 cycles of Geosat/Exact Rep...

The purpose of this observational study was to determine the circulating leukocyte subset response to completing the 2013 Hotter'N Hell Hundred recreational 164-km road cycle event in a hot and humid environmental condition. Twenty-eight men and four women were included in this study. Whole blood samples were obtained 1-2 hours before (PRE) and immediately after (POST) the event. Electronic siz...