Abstract Background Endometrial cancer (UCEC) is one of the most common gynecological malignancies. We previously found that overexpression G protein ? subunit 14 (GNA14) promoted UCEC growth. Krüppel-like factor 7 (KLF7) acts as an oncogene in various types, whereas connection between GNA14 and KLF7 unclear. herein explored involvement GNA14/KLF7 development. Methods Clinical relevance GNA14, ...

Purpose: To investigate the function and interaction of heat-shock cognate protein 70 (Hsc70) potassium voltage-gated channel subfamily A member 5 (KCNA5) in polycystic ovary syndrome (PCOS).Methods: Quantitative reverse transcription polymerase chain reaction (qRT-PCR) western blot were used to measure Hsc70 KCNA5 expression PCOS. The effect on granulosa cell apoptosis was determined by flow c...

Comprehensive analysis of hepatocellular carcinoma 3D models revealed enhanced penetrative siRNA delivery by a nanodiamonds compared to liposomes. Nanodiamonds were able improve siRNA's gene knockdown and anti-cancer effects in tumor models.

Abstract Background LncRNA can regulate gene at various levels such as apparent genetics, alternative splicing, and regulation of mRNA degradation. However, the molecular mechanism in cholangiocarcinoma is still unclear. This deserves further exploration. Methods We investigated expression AGAP2-AS1 32 CCA tissues two cell lines. found a which induced by SP1 has not been reported CCA, Knockdown...