The RM1 model for the lanthanides is parameterized for complexes of the trications of lanthanum, cerium, and praseodymium. The semiempirical quantum chemical model core stands for the [Xe]4fn electronic configuration, with n =0,1,2 for La(III), Ce(III), and Pr(III), respectively. In addition, the valence shell is described by three electrons in a set of 5d, 6s, and 6p orbitals. Results indicate...

A patient with end-stage renal disease (ESRD) on hemodialysis presented with fever, anorexia, and nausea shortly after starting oral lanthanum carbonate for phosphate control. Gastric and duodenal biopsies demonstrated diffuse histiocytosis with intracellular aggregates of basophilic foreign material. Transmission electron microscopy, an underutilized diagnostic test, revealed the nature of the...

The majority of patients with end-stage renal disease have hyperphosphataemia, which is associated with significant morbidity and mortality. Lanthanum carbonate has been introduced as a new treatment modality to lower serum phosphorus. But there has been ongoing concern about lanthanum accumulation in tissues, especially in liver. We describe the case of a woman with pre-existing liver disease,...

Nonsense codon suppression for unnatural amino acid incorporation requires the preparation of a suppressor aminoacyl-tRNA. Chemical acylation strategies are general but inefficient and arduous. A recent report (J. Am. Chem. Soc. 2007, 129, 15848) showed acylation of RNA mediated by lanthanum(III) using amino acid phosphate esters. The successful implementation of this methodology to full-length...

In this report intercellular material in developing cartilage and between reaggregating cartilage cells has been examined with lanthanum staining (3, 7, 13, 16) . The proteinpolysaccharides of cartilage have been extensively studied by biochemical methods (2, 8-10, 18-21), and proteinpolysaccharide extracted from cartilage has been shown to precipitate with lanthanum (2) . The lanthanum-stainin...

철(III)과 란타넘(III)이 혼합된 황산용액에서 황산나트륨에 의한 란타넘 복염의 침전 및 분리를 조사했다. 복염 침전에 영향을 줄 수 있는 여러 요인 중 황산나트륨 란타넘(III)의 농도, 반응온도 시간, 그리고 철(III) 농도에 대해 용액 Na+, SO42- 이온 란타넘(III) 농도가 높을수록 희토류 침전률이 증가했고, 반응온도가 100°C까지 증가함에 따라 황산염 이온의 형성을 촉진해 증가했다. 또한 반응시간이 증가할수록 철(III)의 감소해 3시간 이후에는 거의 침전되지 않았고, 농도는 큰 미치지 않았다. 황산용액에 황산나트륨을 첨가하면 란타넘(III)을 선택적으로 침전시켜 분리할 있다.

We have determined the crystal structures of complexes of phosphoinositide-specific phospholipase C-delta1 from rat with calcium, barium, and lanthanum at 2.5-2.6 A resolution. Binding of these metal ions is observed in the active site of the catalytic TIM barrel and in the calcium binding region (CBR) of the C2 domain. The C2 domain of PLC-delta1 is a circularly permuted topological variant (P...