Labile plasma iron (LPI) represents a component of non-transferrin-bound iron (NTBI) that is both redox-active and chelatable, capable of permeating into organs and inducing tissue iron overload. It appears in various types of hemosiderosis (transfusional and non-transfusional) and in other iron-overload conditions. Sustained levels of LPI could over time compromise organ (e.g. heart) function ...

This study aimed to accurately grasp the impact mechanism and change rule of buildings green spaces on land surface temperature (LST), which is great significance for alleviating urban heat islands (UHIs) formulating adaptation measures. Taking Jinan, China, as area, combined multisource remote sensing data were used in this construct an index system influencing factors. We a spatial regression...

The northern latitudes have warmed by about 0.8 C since the early 1970s, but not all areas have warmed equally. Eurasia shows an overall warming trend, while North America exhibits warming at a lower rate and even a slight cooling trend during the last 50 years in the Eastern USA. We analyzed a recently developed satellite normalized di erence vegetation index (NDVI) data set (July 1981 to Dece...

Abstract Central Sulawesi Province is one of the areas in Indonesia that prone to large earthquakes. Balaroa, Petobo, and Sibalaya were among most fatalities damaged facilities infrastructure due earthquake on September 28th 2018. Around Balaroa Village, besides huge damages Perumnas Housing, area around housing was also affected, for example Jamur, Kelor, Labu streets, many houses buildings da...

Axillary lymph node involvement is an important prognostic factor for breast cancer survival but is confounded by the number of nodes examined. We compare the performance of the log odds prognostic index (Lpi), using a ratio of the positive versus negative lymph nodes, with the Nottingham Prognostic Index (NPI) for short-term breast cancer specific disease free survival. A total of 1818 operabl...

Shiga toxin (Stx), an AB5 toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells whereas LPLs with small head groups do not. Lysophosphatidylinositol (LPI 18:0), the most efficient LPL with the largest head gro...

The solute carrier family 7A member 7 gene (SLC7A7) encodes the light chain of the heterodimeric carrier responsible for cationic amino acid (CAA) transport across the basolateral membranes of epithelial cells in intestine and kidney. Mutations affecting SLC7A7 cause lysinuric protein intolerance (LPI), a multiorgan disorder with clinical symptoms that include visceromegaly, growth retardation,...