نتایج جستجو برای: lawsone
تعداد نتایج: 154 فیلتر نتایج به سال:
A highly efficient and straightforward three-component cascade reaction was developed to synthesize benzo[g]imidazo[1,2-a]quinolinedione derivatives from heterocyclic ketene aminals (HKAs), aldehydes, and 2-hydroxy-1,4-naphthoquinone (HNQ) via Et(3)N-catalyzed tandem [3 + 2 + 1] annulation under solvent-free conditions. The reactions were very mild, convenient and highly regioselective to form ...
A series of 3-substituted-2-hydroxy-1,4-naphthoquinone derivatives with a variety side chains were successfully synthesized by Mannich reaction 2-hydroxy-1,4-naphthoquinone (lawsone) selected amines and aldehydes. All substances (1–16) evaluated for in-vitro antimalarial activity against strains Plasmodium falciparum microculture radioisotope technique. Bioassay data revealed that ten (1–8, 11 ...
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