نتایج جستجو برای: lc qtof msms
تعداد نتایج: 30214 فیلتر نتایج به سال:
Abstract We describe an analytical method for the identification, mapping and relative quantitation of glycopeptides from SARS-CoV-2 Spike protein. The may be executed using a LC-TOF mass spectrometer, requires no specialized knowledge glycan analysis exploits differential resolving power reverse phase HPLC. While this separation technique resolves peptides with high efficiency, glycans are res...
The LQFM05 is a prototype drug designed for treatment of psychiatric disorders, such as schizophrenia, exhibiting anxiolytic- and antidepressant-like (12 or 24 µmol/kg) effects in classical behavioral tests. In order to evaluate its pharmacokinetic properties, liquid chromatography method coupled quadrupole time flight mass spectrometry system (LC-QTOF/MS) was developed fully validated analysis...
Marginal structural models (MSMs) allow estimation of effect modification by baseline covariates, but they are less useful for estimating effect modification by evolving time-varying covariates. Rather, structural nested models (SNMs) were specifically designed to estimate effect modification by time-varying covariates. In their paper, Petersen et al. (Am J Epidemiol 2007;000:000–00) describe h...
Questions concerning longitudinal data quality and reproducibility of proteomic laboratories spurred the Protein Research Group of the Association of Biomolecular Resource Facilities (ABRF-PRG) to design a study to systematically assess the reproducibility of proteomic laboratories over an extended period of time. Developed as an open study, initially 64 participants were recruited from the bro...
Salvia species are known for their anti-fungal and anti-acetylcholinesterase (AChE) activity. Metabolomics is defined as a comprehensive quantitative qualitative analysis of large-scale metabolites. In this study, besides determining synergistic antifungal activities selected (S. cryptantha Montbret & Aucher ex Benth., S. tchihatcheffii (Fisch. C. A. Mey.) Boiss., officinalis L., virgata Ja...
Autoimmune uveitis is a blinding disease presenting with autoantibodies against eye-specific proteins as well as autoagressive T cells invading and attacking the immune-privileged target tissue retina. The molecular events enabling T cells to invade and attack the tissue have remained elusive. Changes in membrane protein expression patterns between diseased and healthy stages are especially int...
Authors 4 Christelle Margoum, Céline Guillemain, Xi Yang, Marina Coquery 5 a Irstea, UR MALY, 5 rue de la Doua, CS 70077, F-69626 Villeurbanne Cedex, France 6 b State Key Laboratory of Pollution Control and Resource Reuse, Nanjing University, 210093 Nanjing, China 7 *corresponding author Tel. +33472208711; fax: +33478477875; E-mail address: [email protected] 8 9 10 Abstract 11 Stir b...
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