BACKGROUND Although conventional magnetic resonance imaging (MRI) could provide excellent detection of morphological changes in the diagnosis of lumbar disc degeneration (LDD), it has some difficulties in discriminating minimal changes associated with early LDD before morphological or clinical alterations. Therefore, newer MRI techniques have emerged for investigation of early LDD. OBJECTIVES...

Lhermitte-Duclos disease (LDD) is a rare cerebellar disorder believed to be pathognomonic for Cowden syndrome. Presently, the only known etiology is germline PTEN mutation. We report a 41-yr-old white female diagnosed with LDD and wild-type for PTEN. Exome sequencing revealed a germline heterozygous EGFR mutation that breaks a disulfide bond in the receptor's extracellular domain, resulting in ...

The spatial variability of three indicators of learning and developmental disability (LDD) was assessed for Cape Cod, Massachusetts. Maternal reports of receiving special education services, attention deficit hyperactivity disorder, and educational attainment were available for a birth cohort from 1969-1983. Using generalized additive models and residential history, maps of the odds of LDD were...

BACKGROUND AND OBJECTIVES Many clinicians believe that low-dose dopamine (LDD) [2 micro g/kg/min] increases renal blood flow (RBF) and medium-dose norepinephrine (MD-NE) [0.4 micro g/kg/min] decreases RBF. They also believe that MD-NE might induce mesenteric and/or coronary ischemia. In fact, the effects of these drugs on renal and vital organ blood flow are poorly understood. The aim of this s...

Mục tiêu: Mô tả kết quả nội soi điều trị phối hợp với thuốc ức chế bơm proton ở bệnh nhân xuất huyết tiêu hóa (XHTH) do loét dạ dày tá tràng (LDD-TT). Phương pháp: Nghiên cứu hồi và tiến về can thiệp các LDD-TT bị XHTH trong 23 tháng từ đầu 1/2020 đến hết 11/2022 48 tại viện Nhật Tân, tỉnh An Giang. Kết quả: Bệnh nam mắc có biến chứng nhiều hơn nữ tỷ số 5:1. lứa tuổi 58-84 muộn 22-94. Khi phân ...

This paper examines the design of a 32-b GaAs Fast RISC microprocessor (F-RISC/I). F-RISC/I is a single chip GaAs HMESFET processor targeted for implementation on a multichip module (MCM) together with cache memories. The CPU architecture, circuit design, implementation, and testing are optimized for a seven-stage instruction pipeline implemented with GaAs super-buffered FET logic (SBFL). We ha...

OBJECTIVE We recently reported the association of the Sp1 site polymorphism of the COL1A1 gene with lumbar disk disease (LDD). In the present study we searched for a different polymorphism of the COL1A1 gene (which is usually not in linkage disequilibrium with the Sp1 site) in subjects with LDD. DESIGN Blood was collected from 24 Greek army recruits, aged 29+/-7.6 years, with LDD, and 66 heal...

BACKGROUND We report a case and review the recent literature describing 36 patients with both Lhermitte-Duclos disease (LDD) and Cowden disease (CD). Lhermitte-Duclos disease, or dysplastic gangliocytoma, is a benign hamartomatous condition involving the cerebellum. The presenting symptoms are usually headaches, gait ataxia, and symptoms of lower cranial nerve involvement. Cowden disease is a r...

OBJECTIVE Lumbar disc degeneration (LDD) is a serious social and medical problem which has been shown to be highly heritable. It has similarities with peripheral joint osteoarthritis (OA) in terms of both epidemiology and pathologic processes. A few known genetic variants have been identified using a candidate gene approach, but many more are thought to exist. GDF5 is a gene whose variants have...

BACKGROUND Myocardial stunning is an important sequela of acute coronary syndromes and its determination might affect decisions on defibrillator implantation and assist devices after myocardial infarction (AMI). The aim of the study was to evaluate and compare the sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of cardiac magnetic resonance imaging...