Cypermethrin was administered to Heteropneustes fossilis in chronic concentration to determine lesion of liver as indicators of tissue damage. The cypermethrin dose used was 1/4 of 96 hr LC50. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and disposition of yellow brown grains at different time of exposure viz; 20th, 30th, 40th and 60th ...

INTRODUCTION PATHOPHYSIOLOGY Hematopoietic Syndrome Gastrointestinal Syndrome Neurovascular Syndrome DETERMINANTS OF RADIATION EFFECTS ON HUMANS Lethality Curve Influence of Trauma on LD50 Effect of Clinical Support on the LD50 Dose Effect Curve CLINICAL ASPECTS OF THE US CRITICALITY EXPERIENCE Clinical Course of the Criticality Cases CURRENT TREATMENT OF ACUTE RADIATION SYNDROME Supportive Car...

Malaria is considered a major health problem in Iran. There are different methods for vector control. In this study we tested the larvicidal effects of some Iranian plants. The methanolic extracts of 11 plants were prepared with percolation method. The larvicidal activities of them against malaria vector, Anopheles stephensi were studied using World Health Organization standard method. All LC50...

Pyrethroid resistance in bed bugs, Cimex lectularius, has prompted a change to combination products that include a pyrethroid and a neonicotinoid. Ten populations of bed bugs were challenged with two combination products (Temprid SC and Transport GHP). Susceptibility of these populations varied, with the correlated response of the two products indicating cross resistance. We imposed selection o...

Marwan Saad Azzubaidi *, Anil Kumar Saxena , Ahmed Ghazi Alattraqchi 3 and Abualrahman Mohammed Abdualkader 4 1 Department of Basic Medical Sciences, Faculty of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia. 2 Department of Basic Medical Sciences, Faculty of Medicine, International Islamic University Malaysia, Kuantan, Malaysia. 3 Biochemistry Unit, Faculty of Medicine,...

Cadmium is a known renal toxin. The cytotoxic effect of cadmium chloride (CdCl2) was evaluated on renal inner medullary collecting duct cells (mIMCD3). The 24 hr LC50 value for CdCl2 in mIMCD3 cells was 40 µM. The present study showed that mIMCD3 cells were sensitive to CdCl2 exposure.

We have conducted the first in-vivo experiments in pencilbeam irradiation, a new synchrotron radiation technique based on the principle of microbeam irradiation, a concept of spatially fractionated high-dose irradiation. In an animal model of adult C57 BL/6J mice we have determined technical and physiological limitations with the present technical setup of the technique. Fifty-eight animals wer...

Juvenile shrimps (Penaeus monodon) weighing about 15-20 gms were procured from the grow-out ponds and reared under laboratory conditions. They were challenged with Vibrio parahaemolyticus MTCC 451 and their LD50 value was evaluated. The ascorbic acid and the histamine activity of both the control and experimental groups were assessed. The results showed a marked decline in both the parameters a...

Pyrethroids are widely used insecticides that may seriously harm aquatic organisms. Being strongly hydrophobic, pyrethroids in solution occur only in short pulses but may be retained in sediments for longer periods. Consequently, most studies consider the chronic exposure of sediment dwelling organisms. We collected data from 16 studies to determine effect thresholds for stream macroinvertebrat...

The acute toxicity of Nuvan to the grass carp Ctenopharyngodon idella was determined using static and continuous flow through system for 24, 48, 72 and 96 hr. The median lethal concentration (LC50) values were 13.1, 10.9, 9.8 and 6.5 mg l(-1) respectively in static system and 10.7, 9.5, 8.0 and 7.5 mg l(-1) respectively in continuous flow through system. A reduction in oxygen consumption is obs...