A fatal case of agranulocytosis due to chlorpromazine is reported. Mechanisms other than immunological are generally believed to be responsible for chlorpromazine-induced agranulocytosis. However, the demonstration of a drug-specific leuco-agglutinin in the serum of this patient suggests that an immunological mechanism was responsible for the agranulocytosis.

The autoradiographic pattern of anterograde labeling as a result from injections with tritiated amino acids is compared to the labeling of efferents with Phaseolus vulgaris leuco-agglutinin after lectin injections in the same nucleus visualized by immunohistochemical methods. This comparison is made for efferents from the ventromedial hypothalamic nucleus to the amygdaloid body.

Electrosynthesis can be carried out in emulsions formed in situ via sonication of otherwise immiscible liquid/liquid systems. The basic physical principles underlying these experiments are introduced and illustrated via three examples: the electroreduction of liquid olefins, the Kolbe electrooxidation, and the electrogeneration of leuco-methylene green.

Omphalone, a new antibiotic, cytotoxic, and phytotoxic pigment has been isolated from fermentations of a Canadian strain of Lentinellus omphalodes. Its structure has been established as 2-(4-methylfuran-2-yl)-1,4-benzoquinone (1) by spectroscopic investigations and conversion into leuco-acetate 2.

© 2012 Keum et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Novel Fischer’s Base Analogous of Leuco-TAM and TAM Dyes – Synthesis and Spectroscopic ...

Customising PRESAGE® for diverse applications T Juang, J Newton, M Niebanck, R Benning, J Adamovics and M Oldham 2013 J. Phys.: Conf. Ser. 444 012029 PRESAGE® is a solid radiochromic dosimeter consisting of a polyurethane matrix, a triarylmethane leuco dye, and a trihalomethane initiator. Varying the composition and/orrelative amounts of these constituents can affect the dose sensitivity, post-...

IN a previous paper by Morgan, Stewart and Hopkins [1922] it was shown that " xanthine oxidase " acts as a typical dehydrase in the sense of Wieland. Tissue preparations which contain the enzyme oxidise the bases hypoxanthine and xanthine to uric acid anaerobically in the presence of methylene blue, the dye being reduced to its colourless leuco-compound. The use of this anaerobic technique, com...

Nitella cells were exposed to various oxidants and reductants, to determine their effect upon the bioelectric potential. These included five systems, with an E(h) range from +0.454 v. to -0.288 v., a total range of 0.742 v. When proper regard was given to buffering against acidity changes, and concentration changes of Na or K ions in the oxidized and reduced forms, no significant effect upon th...

The recent outbreak of Zika virus (ZIKV) infection in the Americas and its devastating impact on fetal development have prompted the World Health Organization (WHO) to declare the ZIKV pandemic as a Public Health Emergency of International Concern. Rapid and reliable diagnostics for ZIKV are vital because ZIKV-infected individuals display no symptoms or nonspecific symptoms similar to other vir...