OBJECTIVES We sought to determine, in a large series of patients with right atrial isomerism, factors associated with mortality. BACKGROUND Right atrial isomerism is associated with complex congenital heart disease and high morbidity and mortality. METHOD All data from patients diagnosed with right atrial isomerism between January 1970 and March 1996 were reviewed. RESULTS A total of 91 c...

High bromine containing dimers of tetrabromoanthra- p -quinodimethane as appealing building-blocks for organic synthesis. Thorough study their isomerism and optoelectronic properties.

We report the case of a 37-year-old man who suffered from biventricular failure due to left isomerism, inferior vena cava interruption with azygos vein continuation, bilateral superior vena cava, double outlet of right ventricle, complete atrioventricular septal defect, pulmonary stenosis, and isolated dextrocardia. Heart transplantation in patients with systemic venous anomalies often requires...

Revealing structural isomerism in nanoparticles using single-crystal X-ray crystallography remains a largely unresolved task, although it has been theoretically predicted with some experimental clues. Here we report a pair of structural isomers, Au38T and Au38Q, as evidenced using electrospray ionization mass spectrometry, X-ray photoelectron spectroscopy, thermogravimetric analysis and indispu...

Status Last revised 1993 Previous titles/other references Clinical Investigation of Chiral Active Substances/ III/3501/91 Additional Notes This note for guidance considers active substances with one or more stereogenic centres which display chirality but not constitutional isomerism or cis/trans isomerism. It should be read in conjunction with Directive 65/65/EEC as amended and Directive 75/318...

A 22 month old male infant with isomerism of the right atrial appendages (associated with a complete atrioventricular septal defect, double outlet right ventricle, and pulmonary valve stenosis) died from pneumococcal septicaemia after a 36 hour illness. He had not been given penicillin prophylaxis. Asplenia was confirmed at necropsy. In a survey of 50 paediatric cardiologists in the United King...

6-Hydrazinonicotinic acid (HYNIC, 1) is a well-established bifunctional technetium-binding ligand often used to synthesise bioconjugates for radiolabelling with Tc-99m. It is capable of efficient capture of technetium at extremely low concentrations, but the structure of the labelled complexes is heterogeneous and incompletely understood. In particular, it is of interest to determine whether, a...