In order to evaluate the effect of liothyronine formulated by Iran Hormone Co.(LT3,IH), 20 patients with primary hypothyroidism received 25mg LT3-IH daily. Another 40 hypothyroids were randomly divided into 4 groups and entered a double blind clinical trail. Two groups received 37.5 and 50mg LTrIH and other two groups took 37.5 and 50mg Cytomel (LTr SKF). Serum T4, T3 and TSH concentratio...

Thyroid gland is an essential endocrine that present in the human body. This review highlights production, regulation and disease conditions of thyroid hormones. The controlled with help hypothalamus pituitary brain. production hormones involves five main steps such synthesis thyroglobulin (TG), iodide uptake, iodination thyroglobulin, storage release. two important produced by are Thyroxine (T...

The variations of glucose 6-phosphate dehydrogenase (G6PD) activity in different brain regions of normal, hypo- and hyperthyroid rats were investigated. Hypo- and hyperthyrodism were experimentaly induced by administration of methimazol and liothyronine, respectively. In normal rats, midbrain had the minimum (70 mU/mg) and cerebral cortex the maximum (349 mU/mg) G6PD activity. Hyperthyrodism in...

Since the introduction of sensitive assays for serum thyroid-stimulating hormone (TSH) clinicians have advised hypothyroid patients to adjust dose levothyroxine (L-T4) in order achieve a normal TSH. A minority are dissatisfied with this treatment strategy and experience symptoms. Some indirect evidence suggests that TSH may not necessarily reflect euthyroidism at tissue level treated L-T4. Incr...

in order to evaluate the effect of liothyronine formulated by iran hormone co.(lt3,ih), 20 patients with primary hypothyroidism received 25mg lt3-ih daily. another 40 hypothyroids were randomly divided into 4 groups and entered a double blind clinical trail. two groups received 37.5 and 50mg ltrih and other two groups took 37.5 and 50mg cytomel (ltr skf). serum t4, t3 and tsh concentrations and...

Only two of the early genes of bacteriophage T7 were found to play a significant role in exclusion of superinfecting bacteriophage T3 particles; genes 0.3 and 1. Protein synthesis by the preinfecting phage particle was not required for efficient exclusion. These findings are discussed with regard to the known functions of these genes during T7 development.