After fluid resuscitation, vasoactive drug treatment represents the major cornerstone for correcting any major impairment of the circulation. However, debate still rages as to the choice of agent, dose, timing, targets, and monitoring modalities that should optimally be used to benefit the patient yet, at the same time, minimize harm. This review highlights these areas and some new pharmacologi...

Abstract In a setting in which an agent has behavioral bias that causes underestimation or overestimation of the health consequences sin goods consumption, paper studies how social planner can affect demand such through education and taxation. When only optimistic consumers are present, depending on elasticity good with respect to taxation, two instruments be substitutes complements. heterogene...

We examined seven 1-d diet records kept during 1 y by 272 men and women instructed to follow a lipid-lowering diet while participating in a clinical trial of pravastatin, a new 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The mean percentage of calories from total fat and saturated, unsaturated, and monounsaturated fatty acids was similar throughout the year even though ...

Liposomes are spherical, self-closed structures formed by lipid bilayers that can encapsulate drugs and/or imaging agents in their hydrophilic core or within their membrane moiety, making them suitable delivery vehicles. We have synthesized a new liposome containing gadolinium-DOTA lipid bilayer, as a targeting multimodal molecular imaging agent for magnetic resonance and optical imaging. We sh...

conclusions contrast-agent-induced nephropathic changes are more closely related to the magnitude of lipid peroxidation than protein oxidation. results compared with the control group, groups cin and n + cin had significantly higher urea and lhp levels (p < 0.05 and p < 0.001, respectively) and significantly lower cu, zn-sod activity and creatinine clearance (p < 0.05). there was no statistical...