abstract objective: cancer is the second cause of death worldwide, among them liver cancer is the fifth most important malignancy. the aim of this study was to investigate chemopreventive activity of berberis vulgaris fruit extract in  hepatocarcinogenesis  sprague dawley rats. materials and methods: fourty-four sprague dawley rats (6-8 weeks old, 150-250g) were divided into normal and cancerou...

Introduction: Noninvasive magnetic resonance imaging (MRI) and targeted drug delivery systems, usually referred to as theranostic agents, are being developed to enable detection, site-specific treatment, and long-term monitoring.   Materials and Methods: To elucidate the effects of coating on cellular uptake and biodistribution of n...

common cancer and the third leading cause of cancer-related deaths. A known risk factor for HCC is non-alcoholic fatty liver disease (NAFLD), a continuum hepatic disorders related to obesity metabolic syndrome. AIM: We conducted an observational study identify factors hepatocellular in patients with who came SMHRC Nagpur routine visit. MATERIAL AND METHODS: The included 300 people aged 35 85 ye...

The Effect of Valproic Acid Drug on the Expression SOCS1, SOCS3, JAK1, JAK2, STAT3, STAT5A and STAT5B Genes in HepG2 Cell Line Liver Cancer

Introduction Liver cancer is a common tumor of digestive system. Hepatectomy sometimes results in massive hemorrhage, and intraoperative autotransfusion often required. Material methods Methods: In this basic research, the liver rat model was established, visible tissue surgically removed, blood mice recovered. Results The showed that group had highest recurrence metastasis cancer, lowest group...

conclusions our results suggest that h. parva and h. oculata may be promising therapeutic candidates for the treatment of hcc, following further confirmatory in vivo experiments and clinical trials. results our results showed that h. parva methanolic extracts (250, 500, and 1000 µg/ml) and h. oculata methanolic extracts (200, 400, and 800 µg/ml) increased reactive oxygen species (ros) formation...

SUMMARY Our gastrointestinal tract is colonized by trillions of microbes. There growing recognition that commensal bacteria can promote the development colorectal adenomas and cancer. For example, bacterial plaques are strongly associated with in familial adenomatous polyposis (Science 2018;359:592-597), fusobacterium cancer liver metastasis.(Science 2017;358:1443-1448)

Approximately 50% of patients with primary colorectal carcinoma develop liver metastases. This study investigates the possible molecular discrepancies between cancer (pCRC) and their respective

Viola odorata as a medical herb is used in liver disorders and relieving cancer pain. In the present study, the cytotoxic, antioxidant, and anti-metastatic properties of Viola odorata hydro-alcoholic extract (VOE) were investigated in 4T1 breast cancer model. After treatment of 4T1 breast cancer cells with VOE, cell viability was measured by MTT assay. The implanted mice were treated with diffe...