Background: Rheumatoid arthritis (RA) can be associated to extra-articular manifestations and comorbidities, including hepatic disturbances. It related an underlying viral, metabolic or immune disease, a medical treatment toxicity [1]. Objectives: We aim study liver involvement in group of RA patients. Methods: performed cross sectional 249 patients responding the ACR/EULAR 2010 criteria for di...

Cranial Arteritis With Liver Involvement • An elderly man with cranial nerve palsies was found to have cranial arteritis. Laboratory studies established concurrent liver disease which improved with treatment. The liver and brain stem pathology is discussed. ADDITIONAL

A 19-year-old man presented with painless jaundice for 3 months. He had a 14-year history of recurrent, photosensitive, painful rashes without blistering on exposed areas of the face and hands. Examination revealed icterus, hyperpigmentation, hyperkeratosis, and leathery texture over affected hands with onyncholysis, loss of lunulae, melanonychia, and firm hepatosplenomegaly (Figure 1). Laborat...

Sarcoidosis is a multisystem disease characterized by the presence of non-caseating granulomas in affected organs. Pulmonary involvement is the most common site of disease activity. However, hepatic involvement is also common in sarcoidosis, occurring in up to 70% of patients. Most patients with liver involvement are asymptomatic. Therefore, the majority of cases are discovered incidentally, fr...

Liver involvement was retrospectively evaluated in 137 patients with murine typhus. Fifteen (10.9%) were jaundiced. One patient had been subjected to cholecystectomy after misdiagnosis of acute cholecystitis. Serum aminotransferase levels were abnormal in 48/52 measurements, and there were elevations of > 5-fold in 14 patients. Liver biopsies and/or necropsies from four jaundiced patients showe...

human echinococcosis remains a complex problem that affects several organs. hydatid disease mainly (85%) affects liver as well as lung, and 10% the rest of the body. renal involvement is about 2% while skin hydatidosis is nearly 1%. coincidental involvement of kidney and skin is very rare. we report a 51 year-old female patient with renal and skin (chest wall) hydatid lesions that were excised ...

introduction: the wilson disease is an autosomal recessive disease in which the liver, central nervous system, eyes, blood and other parts of the body involved. timely diagnosis and appropriate treatment of the disease requires awareness of the clinical presentations of this disease in children.methods: this case series study included 62 patients with wilson disease who admitted to children&apo...

Liver involvement was one of the first extraglandular manifestations to be reported in patients with primary Sjögren syndrome (SS). In the 1990s, a study of liver involvement in patients with primary SS integrated the evaluation of clinical signs of liver disease, liver function and a complete panel of autoantibodies. Recent developments in the field of hepatic and viral diseases have significa...

BACKGROUND/AIMS Patients with primary Sjögren's syndrome may present liver involvement. Our goals were to establish the prevalence of abnormal hepatic biochemistries and clinical liver disease in patients with primary Sjögren's syndrome and correlate their presence with other clinical and laboratory features. METHODS Ninety-five patients with diagnosis of primary Sjögren's syndrome were studi...

In the coronavirus disease-2019 (COVID-19) pandemic, which started in 2019 and was caused by severe acute respiratory syndrome-coronavirus-2 virus, clinical course of infection observed a wide range from very mild symptoms to death. Although system lungs are mostly affected COVID-19 infection, other organs systems also affected. The most common fever, cough, fatigue, difficulty breathing, anosm...