نتایج جستجو برای: local anesthetic action
تعداد نتایج: 1119077 فیلتر نتایج به سال:
Effect of cutaneously applied nonionic surfactants and local anesthetic bases on thermal sensations.
With cutaneously applied local anesthetic bases various effects may be observed, such as a decrease in pricking pain and a change in burning, itch, and thermal sensations. These effects occur after skin penetration and may be attributed to the action of the anesthetics on nociceptors and thermoreceptors, i.e., on C and A delta nerve fibers, respectively. As little is known about the pharmacodyn...
Aims and background: The infraclavicular nerve block as a method for anesthesia or analgesia in upper extremities that can be performed under guide of nerve stimulation or ultrasound. One of the adverse reaction to this method is the local anesthetic systemic toxicity that has been decreased when using the ultrasound to avoid intravascular injection. Case report: This case report explains a...
Although beneficial in acute and chronic pain management, the use of local anaesthetics is limited by its duration of action and the dose dependent adverse effects on the cardiac and central nervous system. Adjuvants or additives are often used with local anaesthetics for its synergistic effect by prolonging the duration of sensory-motor block and limiting the cumulative dose requirement of loc...
Amitriptyline, a tricyclic antidepressant agent is used as one of the analgesic drugs in different kinds of pain. In the present study the effect of local (subcutaneous) injection of amitriptyline (50 and 100 µg) on the acute and chronic pain using formalin test, was investigated. Our data show that local injection of amitriptyline to the paw receiving formalin, causes a decrease in pain in bot...
Local anesthetic solutions were applied suddenly to the outside of single myelinated nerve fibers to measure the time course of development of block of sodium channels. Sodium currents were measured under voltage clamp with test pulses applied several times per second during the solution change. The rate of block was studied by using drugs of different lipid solubility and of different charge t...
Abstract Backgroung: Recent studies have shown that Tramadol has local anesthetic effects in addition to its classical analgesic effect. In this study, the local anesthetic and postoperative analgesic effects of Tramadol were compared with those of Lidocaine in minor surgeries under local anesthesia. If the efficacy of Tramadol in this regard is proven, it will make considerable advances in th...
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