OBJECTIVE To assess whether an early GnRH antagonist start leads to better follicular synchronization and an improved clinical pregnancy rate (CPR). METHODS A retrospective cohort study. A total of 218 infertile women who underwent IVF between January 2011 and February 2013. The initial cohort (Cohort I) that underwent IVF between January 2011 and March 2012 included a total of 68 attempted I...

The recent introduction of GnRH antagonists in assisted reproductive technologies (ART) has simplified ovarian stimulation (1). This is mainly due to the immediate mode of antagonist action, which allows their administration during the follicular phase, when the inhibition of premature LH surge is required. In this way, the prolonged period of downregulation, necessary in the long agonist proto...

background: the differential efficacy between long gnrh agonist with antagonist can partly be due to the preexisting differences in the early antral follicles before ovarian stimulation. objective: to compare the effect of pretreatment by estradiol with gnrh antagonist on antral follicular size coordination and basal hormone levels in gnrh antagonist protocol. materials and methods: on cycle da...

BACKGROUND General concern is that the pregnancy rate is higher with GnRH-agonist as a protocol of pituitary suppression. GnRH-antagonist protocol provides a shorter period of administration and an easy flexible protocol. OBJECTIVE In this study, the outcomes of GnRH agonist and antagonist in ICSI cycles are compared in normo responder patients. MATERIALS AND METHODS In this randomized clin...

Background & aim: There are conflicting results regarding the benefit of gonadotropin releasing hormone (GnRH) agonist treatment on frozen embryo transfer (FET) outcome. No study was found to compare pregnancy outcome between patients undergoing short and long acting types of GnRH agonist for FET cycles. This study aimed to assess the effectiveness of short and long ac...

Objectives: There are various ovarian stimulation protocols for in vitro fertilization (IVF). Particularly for Poly-cystic Ovarian Syndrome (PCOS) patients an optimized protocol of pituitary FSH and LH down regulating gonadotropin-releasing hormone agonist (GnRHa) medication without complications is still a challenge. Methods: We retrospectively compared the primary endpoint of an ultra-long an...

Objective To evaluate the effects of different ovarian stimulation protocols on in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes infertile women with adenomyosis. Methods We carried out a retrospective cohort study among adenomyosis receiving IVF/ICSI treatment, including 257 fresh embryo transfer (ET) cycles and 305 frozen (FET) cycles. In ET cycles, ultra-long, long...

Background: Regarding the develops of treatment and management of infertility during recent three decades, success of these methods is limited. Therefore, this study tried to show how corticosteroid therapy improves the results of ICSI. Materials and Methods: This semi clinical trail studywithout control group, including infertile women were candidate to ICSI of Kosar infertility center in urmi...

OBJECTIVE To evaluate the effectiveness of GnRH antagonist multiple dose protocol applied during early and late follicular phase (MDP-EL) in comparison with standard GnRH agonist luteal long protocol (LP) in each non-obese and obese polycystic ovary syndrome (PCOS) women undergoing IVF. METHODS Two hundred eleven infertile women with PCOS were recruited and randomized to undergo either GnRH a...

BACKGROUND This study compared rates of pregnancy and in vitro fertilization (IVF) parameters in subjects stimulated with follicle stimulating hormone (FSH) plus either recombinant human luteinizing hormone (r-LH) or human menopausal gonadotropin (hMG) in a long gonadotropin releasing hormone (GnRH) agonist IVF protocol. MATERIALS AND METHODS This cohort study enrolled patients who underwent ...