We report development of the first genetically encoded bioluminescent indicator for membrane voltage called LOTUS-V. Since it is bioluminescent, imaging LOTUS-V does not require external light illumination. This allows bidirectional optogenetic control of cellular activity triggered by Channelrhodopsin2 and Halorhodopsin during voltage imaging. The other advantage of LOTUS-V is the robustness o...

Neural circuitry formation depends on the molecular control of axonal projection during development. By screening with fluorophore-assisted light inactivation in the developing mouse brain, we identified cartilage acidic protein-1B as a key molecule for lateral olfactory tract (LOT) formation and named it LOT usher substance (LOTUS). We further identified Nogo receptor-1 (NgR1) as a LOTUS-bindi...

Non-alcoholic fatty liver disease (NAFLD) is emerging as the most common liver disease in industrialized countries. The discovery of food components that would ameliorate NAFLD is therefore of interest. Lotus root, the edible rhizome of Nelumbo nucifera, contains a high level of polyphenolic compounds, and several health-promoting properties of lotus root have been reported. The present study e...

Genomic resources such as single nucleotide polymorphism (SNPs), insertions and deletions (InDels) and SSRs (simple sequence repeats) are essential for crop improvement and better utilization in genetic breeding. However, the resources for the sacred lotus (Nelumbo nucifera Gaertn.) are still limited. In the present study, to dissect large-scale genomic molecular marker resources for sacred lot...

Lotus japonicus is a well-characterized model legume widely used in the study of plant-microbe interactions. However, datasets from various Lotus studies are poorly integrated and lack interoperability. We recognize the need for a comprehensive repository that allows comprehensive and dynamic exploration of Lotus genomic and transcriptomic data. Equally important are user-friendly in-browser to...

Let G be a (p, q) graph. Let k be an integer with 2 ≤ k ≤ p and f from V (G) to the set {1, 2, . . . , k} be a map. For each edge uv, assign the label |f(u) − f(v)|. The function f is called a k-difference cordial labeling of G if |νf (i) − vf (j)| ≤ 1 and |ef (0) − ef (1)| ≤ 1 where vf (x) denotes the number of vertices labelled with x (x ∈ {1, 2 . . . , k}), ef (1) and ef (0) respectively den...

For any non-trivial abelian group A under addition a graph $G$ is said to be $A$-textit{magic}  if there exists a labeling $f:E(G) rightarrow A-{0}$ such that, the vertex labeling $f^+$  defined as $f^+(v) = sum f(uv)$ taken over all edges $uv$ incident at $v$ is a constant. An $A$-textit{magic} graph $G$ is said to be $Z_k$-magic graph if the group $A$ is $Z_k$  the group of integers modulo $k...

Lotus leaves have become an icon for superhydrophobicity and self-cleaning surfaces, and have led to the concept of the 'Lotus effect'. Although many other plants have superhydrophobic surfaces with almost similar contact angles, the lotus shows better stability and perfection of its water repellency. Here, we compare the relevant properties such as the micro- and nano-structure, the chemical c...