OBJECTIVES/HYPOTHESIS Vocal cord scar formation and laryngotracheal stenosis (LTS) are challenging problems for otolaryngologists. Sendai virus (SeV) vectors have been shown to transduce airway epithelium efficiently, and are thus ideal for modulating airway wound-healing therapy. To assess the potential utility of SeV gene therapy for laryngotracheal diseases, we established a novel LTS model ...

As the mechanisms for learning and memory are elucidated, modulation of learning and memory becomes a central issue. We studied the modulation of learning and memory by investigating the circadian regulation of short- and long-term sensitization of the siphon withdrawal reflex in Aplysia. We found that Aplysia exhibited diurnal and circadian rhythms of long-term sensitization (LTS) with signifi...

Early detection of invasive species is critical for effective biocontrol to mitigate potential ecological and economic damage. Laser transmission spectroscopy (LTS) is a powerful solution offering real-time, DNA-based species detection in the field. LTS can measure the size, shape and number of nanoparticles in a solution and was used here to detect size shifts resulting from hybridization of t...

SUMMARY This paper proposes an event-based transition system called A-LTS. An A-LTS is a simple system consisting of two agents, a basic program and a monitor. The monitor observes the behavior of the basic program and if the behavior matches some pre-defined pattern, then the monitor interrupts the execution of the basic program and possibly triggers the execution of another specific program. ...

BACKGROUND Laryngotracheal stenosis (LTS) can cause persistent or recurrent airway obstruction. Although there is extensive literature on surgical techniques to treat LTS at onset, there are few techniques described for complex adult LTS after failed prior airway surgery. We describe a procedure used successfully in 3 patients who required structural augmentation for complex LTS. METHODS Pati...

With the inception of the web now being more than 20 years ago, many web-based learning technology systems (LTS) have had a long life and have undergone many changes, both affecting content and infrastructure technologies. A change factor model can capture the various factors causing LTS to change. Methods for change-aware design of LTS have been suggested. The purpose of this investigation is,...

Repetitive, unilateral stimulation of Aplysia induces long-term sensitization (LTS) of ipsilaterally elicited siphon-withdrawal responses. Whereas some morphological effects of training appear only on ipsilateral sensory neurons, others appear bilaterally. We tested the possibility that contralateral morphological modifications may have functional significance. Therefore, we examined whether LT...

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive disease with five-year overall survival (OS) of less than 10%. The longest median OS ever reported for PDAC patients was 54.4 months in the phase III PRODIGE study. aim our study to examine clinico-pathological characteristics Long-Term Survivors (LTS). This a retrospective analysis prospectively maintained surgical and oncologi...

OBJECTIVE: The role of supraglottic airway devices in emergency airway management is highlighted in international airway management guidelines. We evaluated the application of the new generation laryngeal tube suction (LTS-II/LTS-D) in the management of in-hospital unexpected difficult airway and cardiopulmonary resuscitation. METHODS: During a seven-year period, patients treated with a laryn...

We investigate Leifer and Milner RPO approach for deriving efficient (finitely branching) LTS’s and bisimilarities for π-calculus. To this aim, we work in a category of second-order term contexts and we apply a general pruning technique, which allows to simplify the set of transitions in the LTS obtained from the original RPO approach. The resulting LTS and bisimilarity provide an alternative p...