We investigate methods for modelling metabolism within populations of cells. Typically one represents the interaction of a cloned population of cells with their environment as though it were one large cell. The question is as to whether any dynamics are lost by this assumption, and as to whether it might be more appropriate to instead model each cell individually. We show that it is sufficient ...

Designing high performance very large scale integration (VLSI) circuits has become more challenging than ever due to deep sub-micron effects and accelerating time-to-market cycles. With the increasing interconnect delay dominance and strong coupling effects, a small change in the design can cause new timing violations and result in design iterations. At the same time, the industry trend of inte...

Voiced speech is a highly complex process involving coupled interactions between the vocal fold structure, aerodynamics, and acoustic field. Reduced-order lumped-element models of the vocal fold structure, coupled with various aerodynamic and acoustic models, have proven useful in a wide array of speech investigations. These simplified models of speech, in which the vocal folds are approximated...

In this work the transient analysis of a power network excited by indirect lightning is performed directly in time domain. Using the FDTD, we calculate induced currents and voltages in each node for a three-phase power network. The topological analysis of the network where each element (power line and lumped charge) is considered, allows deducing the matrix equation. In this electrical network ...

We discuss various issues concerning the behaviors near the boundary (σ = 0, π) and the midpoint (σ = π/2) of the open string coordinate X(σ) and its conjugate momentum P (σ) = −iδ/δX(σ) acting on the matter projectors of vacuum string field theory. Our original interest is in the dynamical change of the boundary conditions of the open string coordinate from the Neumann one in the translational...

We analyse the fi nancial performance of small German hospitals based on balance sheet data of about 1,000 hospitals in 2007. Measures of fi nancial performance are the earnings before interest, tax, depreciation, and amortisation (EBITDA) and the probability of default (PD). We fi nd that, on average, small hospitals have more fi nancial diffi culties than large ones. However, there is conside...

In the talk we will address the problem of finding an optimal dividend policy for a class of jumpdiffusion processes. The jump component is a compound Poisson process with negative jumps, and the drift and diffusion components are assumed to satisfy some regularity and growth restrictions. With each dividend payment there is associated a fixed and a proportional cost. The aim is to maximize exp...

Any country in the world constantly seeks upgrade every aspect of life and so is network industry. India one them as developing nation to evolve industry although evolution considered be moderate. With growing amount data produced minute need quick access at user end a network, efficient yet exhaustive use cloud resources has become more important than ever. Hence reduce time consumption compli...

We analyse the fi nancial performance of small German hospitals based on balance sheet data of about 1,000 hospitals in 2007. Measures of fi nancial performance are the earnings before interest, tax, depreciation, and amortisation (EBITDA) and the probability of default (PD). We fi nd that, on average, small hospitals have more fi nancial diffi culties than large ones. However, there is conside...

* We are grateful to the many members of the MIT and Harvard economics communities who have generously provided us with insightful conversations, comments on an earlier draft of this paper and practical support. We are particularly indebted to